Resumo Estudo descritivo, de abordagem quantitativa, para avaliar as estratégias realizadas pelo enfermeiro no ambiente escolar de um Centro

As ações de educação em saúde para crianças e adolescentes nas unidades básicas da região de Maruípe no município de VitóriaActions of education health for child and adolescents in the city of Vitória

Objetivo: realizar um levantamento bibliográfico com enfoque nos compostos bioativos que modulam a inflamação na obesidade. Métodos: foram utilizadas as bases de dados Scientific Eletronic Library Online e PubMed, com artigos de revisão e originais, em língua portuguesa e inglesa, publicados entre 2010 e 2019, adotando os seguintes descritores: obesity, inflammation e bioactive compounds. Resultados: alimentos com propriedades funcionais e fontes de compostos bioativos podem auxiliar na modulação de citocinas pró-inflamatórias, como a curcumina no açafrão da terra, as catecolaminas no chá-verde, punicalagina na romã, a β-glucana na aveia e os polifenóis no azeite de oliva. Tais compostos geralmente atuam inibindo mediadores, como fator nuclear Kappa β e catecol-o-metiltransferase, diminuindo marcadores inflamatórios como fator de necrose tumoral α e as interleucinas (1, 2, 6, 8, e 12). Conclusão: tendo em vista o potencial dos alimentos em modular a inflamação na obesidade, o conhecimento de suas propriedades funcionais é importante por auxiliar os profissionais de Nutrição no planejamento de estratégias para a prevenção e o tratamento da obesidade.

Alkaptonuria is a rare autosomal recessive disorder caused by deficiency in homogentisate 1,2-dioxygenase, which leads to a tissue accumulation of homogentisic acid (HGA). HGA irreversibly deposits in connective tissues, which leads to degeneration of the articular cartilage, leaving these tissues with dark pigmentation, known as ochronosis. Alkaptonuria typically presents with a triad of homogentisic aciduria, ochronosis and ochronotic arthropathy during the third and fourth decade of life. The ochronotic arthropathy is the most impactful complication in the quality of life, even though it virtually impacts every system. There is no effective treatment, so intervention is based on symptoms, maintaining function and pain control while the inevitable deterioration of weightbearing joints progresses. Almost all patients are submitted to arthroplasties of the knee and/or hip. Soon there might be a way to prevent complications, has there are ongoing phase 3 studies to approve a drug that blocks the formation of HGA.

Introduction: The intestinal microbiota has been the subject of research due to its association in physiological and pathological conditions. The production of short chain fatty acids obtained by fermentation of the intestinal microbiota has shown important effects on the gastrointestinal tract, adipose tissue, immune system and nervous system. Objective: This literature review aims to present different nutritional strategies with the potential to modulate the intestinal microbiota by increasing the production of short chain fatty acids. Methods: The research was considered a review work, through a bibliographic survey carried out from the collection of articles in English, published in the PubMed database, in the period from 2013 to 2020. The articles were selected from the descriptors: gut microbiota, soluble fiber, resistent starch, pectin, dietary fiber, short chain fatty acids (SCFA) with the combinations of the Boolean operators “and” and “or”. Studies considered as gray literature were excluded, as well as studies in which the titles were not related to the theme of the proposed research. Results: There are many benefits to consuming foods that may favor the increase of short chain fatty acids. This increase in the gastrointestinal tract is of fundamental importance for the maintenance of intestinal microbiota and prevention of diseases. Some nutritional strategies can be used in clinical therapy, such as increased consumption of fruits, vegetables and whole grains that are plant foods and important sources of fiber. The type of food must be observed, since each one can contain fibers of diverse types. Soluble fiber is the basis for the metabolization of short chain fatty acids and is found in various foods that can be inserted into the food plan, such as: bananas, apples, oats, barley, cooked and cooled potatoes, partially ground seeds, corn, morning cereal, agave, artichoke, asparagus, chicory root, garlic, onion, leeks and wheat. Conclusion: Scientific evidence of the relationship between nutrition, intestinal microbiota and short-chain fatty acid production demonstrates the importance of implementing simple nutritional strategies by health professionals, which can contribute to the modulation of the intestinal microbiota and the development of new perspectives in the development of therapies for prevention and treatment of diseases.