Magnesium sulfate is effective for severe acute asthma treated in the emergency department QUESTION What is the effectiveness of intravenous magnesium sulfate in patients with acute asthma who were treated in the emergency department? DATA SOURCES Studies were identified from the Cochrane Airways Review Group Register, MEDLINE, EMBASE/Excerpta Medica, CINAHL (Cumulative Index to Nursing and Allied Health), and the Cochrane Library. We also manually searched 20 high-quality respiratory journals and bibliographies of relevant articles and contacted authors and content experts. STUDY SELECTION Studies were selected if they were randomized controlled trials or quasi-randomized trials, included adults or children seen at an emergency department with acute asthma, and compared the use of intravenous magnesium sulfate with placebo. DATA EXTRACTION Data on study and patient characteristics, hospital admissions, pulmonary function, vital signs, and adverse events were extracted.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.