The purpose of the study conducted was to know the extent of protection over the cancer associated metabolic syndrome development after administration of ethanol and aqueous extracts of Drosera peltata J.E.Sm against Dalton's ascites lymphoma (DAL) and Ehrlich's Ascites Carcinoma (EAC) bearing mice. Animals were divided into thirteen groups with a normal control, EAC control, DAL control, two groups with standard drug 5-Flurouracil 20mg/kg+ DAL & EAC and eight groups with 250 and 500mg/kg of ethanol and aqueous extracts of D.peltata J.E.Sm + EAC & DAL, for respective cell lines. After 24h of both tumor cell inoculations, animals were treated with extracts, once in a day for 14 days continuously. The indicators for the development of metabolic syndrome such as changes in blood glucose, serum hormone and lipid profile were found with both cell line bearing mice. Both ethanol and aqueous extracts of D.peltata J.E.Sm at doses of 250 and 500mg/kg significantly reduced the elevated blood glucose, hormonal and lipid profile changes. These results confirmed that ethanol and aqueous extracts can stabilize the tumor induced hormonal, blood glucose and lipid profile changes in tumor bearing mice. This effect might be due to the presence of pharmacologically active phytoconstituents in extracts.

The present study was carried out to evaluate the antiarthritic activity of Glycine max seeds in adjuvant induced arthritis in rats. Antiarthritic activity was assessed based on the paw volume, biochemical parameters, haematological parameters and histological parameters. The changes in the above said parameters were reversed by the G.max seed extract administered at the dose of 60 mg/kg orally. Hence further detailed investigation is required to isolate the compound responsible for the antiarthritic activity

The purpose of this study was to measure the antioxidant status of animals treated with 250 and 500 mg / kg doses of ethanol and aqueous extract of Drosera peltata on Erich ascites carcinoma (EAC) inoculated mice. A total of 70 mice were divided into 7 groups, each group with ten mice. The first group received normal food and water for 14 days and was under normal control. The second group also received normal food and water for 14 days, which was cancer control. Third group received 5- flurouracil (20 mg/kg, i.p) for 14 days. Fourth and fifth group animals received 250 and 500 mg / kg of ethanol extracts of D. peltata (EEDP) whereas the sixth and seventh groups of mice received 250 and 500 mg / kg of aqueous extracts of D. peltata (AEDP), orally for 14 days. All the groups were inoculated with EAC (2×106 cells/mouse, i.p.) except Group I, 24 hours before the commencement of the drug treatment. After the completion of treatment, blood was drawn retro-orbitally and sacrificed to isolate the liver, lungs, kidneys, and brain for observing tissue antioxidant status. The parameters analyzed were total protein (TP), catalase (CAT), malondialdehyde (MDA), superoxide dismutase (SOD), peroxidase (P), and glutathione (GSH) from the tissues apart and the protein carbonyl content (PCC) also measured from the blood sample. Treatment with EEDP and AEDP significantly lowers the MDA levels from 23 to 10 mmol/ml in the blood whereas 28 to 4 nm/g tissue isolates the liver, lungs, kidneys, and brain. It also raised the TP, GSH, SOD, CAT, and P levels in the blood and the tissues sample of the cancer cell line inoculated animals, and their levels are maintained similarly to normal group animals. The results proposed that both the extracts of D. peltata retained the various tissue antioxidant statuses in mice with EAC cancer lines.