A retrospective study was performed in 62 cases of Prolonged Fever |PF), 16 were 3 to 6 years old and 46 were 7 to 14 years old, 56.5% were females.Infectious diseases caused 77.4% of all cases of PF, with Typhoid Fever (64.5%), pressumed Viral diseases (10.4%) and Urinary Tract Infection (10.4%) being the most common. There were 2 Collagen-Inflamatory diseases, one case of Drug Fever due to Phenobarbital and no Malignancies. 17.8% of all cases did not have a final diagnosis.There was some relationship bet ween infectious diseases and season of the year. Signs and symptoms were helpful in certain cases, but contradictory in others. Also there was a certain lack

Thirty one patients, aged 4 to 15 years old with Systemic Lupus Eiythematosus (SLE) were evaluated retrospectively in order to analyse the clinical course of the disease. Twenty six patients were female and 5 males. All of them fulffled the criterions stated by the American Rheum atolo gist Academy for the diagnosis of S.L.E. Clinical and laboratory diagnostic parameters were similar to those of adult type. Our patients had mainly articular and cutaneous lessions. Whole survival rates were 68 and 40 per cent at five and ten years respectively. In children with renal lupus lesions the survival rates diminished to 57 and 28 per cent Patients without renal involvement had 90 per cent survival rates along the whole 10 years period. The authors rise the possibility to lower mortality rates, in those patients presenting initially with renal S.L.E. damage, by adding to their treatment other inmunosuppressors to the usually prescribed adrenal steroid derivates, because among 19 patients with such an evidence, only 5/12 (42^ receiving steroids alone survived at 5 years follow up in contrast with 7/7 of those receiving combined schedules.La sobrevida del paciente con Lupus Eritematoso Diseminado (LED) infantil ha sido materia de controversia debido a los diferentes resultados que se ban publicado en los ultimos afios. En efecto, los primeros trabajos 1 -demostraban sobrevidas a 5 afios de 72% y 42% en nifios sin y con compromise renal respectivamente, en cambio publicaciones mas recientes dan sobrevidas de 100% en pacientes con Iesi6n renal 2 .Estos resultados pueden explicarse, en gran medida, por los avances alcanzados en el diagnos-tic© mediante la introduction de nuevas te"cnicas inmunologicas que permiten hacerlo mas precozmente, un mejor manejo de la actividad lupica y por otra parte, el uso de corticosteroides y andbioticos que ha significado controlar en mejor forma la enfermedad y evitar las complicaciones infecciosas que constituyen una de las principles causas de mortalidad en estos pacientes 3 .No obstante estos adelantos, queda aun por resolver el papel que tienen los nuevos tratamientos, especialmente las drogas inmunosupresoras