This was a retrospective study, made at the Hospital das Clinicas University of São Paulo Medical School--Ribeirão Preto from 1956 to 1979 in 500 patients with neurocysticercosis. To our knowledge, this represented the largest sample analysed so far. Clinical manifestations and complemmentary tests were studied. The neurocysticercosis is a serious endemic disease in our region and represented 2.7% of all clinical evaluations by the Neurology Department and 7.5% of all hospital admissions. The most frequent clinical presentations were the epileptic (64.8%), the intracranial hypertension (35.6%), and the meningitic (29%). Radiological study of the skull showed intracranial calcifications suggestive of cysticercosis in 47.6%. The cerebrospinal fluid was abnormal in 81.3%: pleocytosis in 60.9%, increased protein in 49.1% and increased pressure in 29%. The presence of eosinophils occurred in 41.9%, and the Weinberg test was positive in 62,6% of all the cases. It was discussed the utility of the different drugs and the results of the surgical treatment in neurocysticercosis drawing the conclusion that they show no efficacy when analysed at the end of a long follow-up. Since none of the drugs seems to be really efficient, only the sanitary education will be able to control this endemic disease that grasses among us with so somber perspectives.

Seventy extracted single-rooted mandibular premolars were used in this study to determine the length of time needed for bacteria present in natural human saliva to penetrate through three commonly used temporary restorative materials and through the entire root canal system obturated with the lateral condensation technique. Five intact teeth with no decay were used in the negative control group and five teeth with extensive decay in communication with the canal, in the positive control group. The 60 teeth used in the experimental group were divided into three groups. In Group 1, the access cavities of 20 teeth were temporarily restored with gutta percha, in Group 2 with IRM and in Group 3 with Cavit-G. All 70 teeth were mounted individually where the crown was placed in contact with human saliva. All five teeth in the positive control group caused broth turbidity within 24 h. In contrast, broth in the negative control group remained clear throughout the entire experimental period. In the experimental group, the average time for broth contamination of access cavities closed with gutta percha, IRM and Cavit-G was 7.85, 12.95 and 9.80 days, respectively. The Kruskal-Wallis nonparametric test showed significant differences among the groups, while the multiple comparison test showed that the IRM group was statistically better than the gutta percha group when the average lengths of time for contamination were compared (P < 0.05).

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