A contribution to the study of crystalluria: significance in the diagnosis of metabolic and renal diseases ABSTRACT The study of crystalluria is of great importance for the detection of substances of endogenous or exogenous origin that are present inthe urine, to a greater or lesser extent. Urinary sediment crystals can provide valuable answers for the assessment of therapeutic efficacy, as well as congenital and/or acquired pathophysiological conditions. The nature of the observed crystals informs the clinician of the biochemical irregularity of the urine. Crystalluria is of clinical significance only if it has been studied under good test conditions (sample selection, time and storage conditions). Crystalluria interpretations are performed on the basis of the urinary pH determined with statistically significant reliability. When studying crystalluria by light microscopy, it is necessary to provide light polarization or bidirectional illuminationin order to reduce the risk of diagnostic error. Keywords:Urine pH, crystalline precipitation, promoters and inhibitors of crystalluria
NTRODUCTIONCrystalluria implies the presence of crystals in the urine and appears due to the over-saturation of certain electrolytes and/or certain substances, which are most often caused by metabolic disorders, hereditary diseases or drugs.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.