Erik L. M. van Rozendaal scite author profile

Six taxine alkaloids were isolated from Taxus baccata needles and partially separated. An HPLC method for the analysis of the taxine fraction was developed. By NMR and deamination/hydrolysis studies it was established that the taxine fraction consisted mostly of taxicin-I and taxicin-II derivatives in a variable ratio. Four of the six taxine alkaloids isolated have not been reported before. All of the alkaloids were found to be unstable under neutral and basic conditions, and some of them were very easily interconverted.

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Chemotaxonomy of Taxus

Rozendaal

Kurstjens

Beek

et al. 1999

Phytochemistry

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Analysis of pharmaceutically relevant taxoids in wild yew trees from Sardinia

Ballero¹,

Loi²,

Rozendaal

et al. 2003

Fitoterapia

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ANALYSIS OF TAXINES IN TAXUS PLANT MATERIAL AND CELL CULTURES BY HPLC PHOTODIODE ARRAY AND HPLC-ELECTROSPRAY MASS SPECTROMETRY

Theodoridis

Laskaris²,

Rozendaal

et al. 2001

Journal of Liquid Chromatography & Related Technologies

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