Non-coding RNAs (ncRNAs) are involved in the regulation of cell metabolism and neoplastic transformation. Recent studies have tried to clarify the significance of these information carriers in the genesis and progression of various cancers and their use as biomarkers for the disease; possible targets for the inhibition of growth and invasion by the neoplastic cells have been suggested. The significance of ncRNAs in lung cancer, bladder cancer, kidney cancer, and melanoma has been amply investigated with important results. Recently, the role of long non-coding RNAs (lncRNAs) has also been included in cancer studies. Studies on the relation between endometrial cancer (EC) and ncRNAs, such as small ncRNAs or micro RNAs (miRNAs), transfer RNAs (tRNAs), ribosomal RNAs (rRNAs), antisense RNAs (asRNAs), small nuclear RNAs (snRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), competing endogenous RNAs (ceRNAs), lncRNAs, and long intergenic ncRNAs (lincRNAs) have been published. The recent literature produced in the last three years was extracted from PubMed by two independent readers, which was then selected for the possible relation between ncRNAs, oncogenesis in general, and EC in particular.

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During 1994, 20 patients underwent pharmacocavernosometry because of suspected venous leakage. Only two patients showed evident signs of this syndrome. However, in another 10 patients, who did not show cavernosometric signs of venous leakage, cavernosography manifested opacity of the pudendal veins. Therapy for the two above-mentioned cases was surgical ligation of the crural vessels and of the dorsal vein. Short-term results have been substantially satisfactory. Analysing these cases and taking into account the latest bibliographic references, a prevalently functional pathogenesis of venous leakage can be proposed. Pharmacocavernosometry, as a functional diagnostic exam, although limited, could be the best test presently available to diagnose this syndrome. Cavernosography, being a more anatomic exam, could appear much less significant. The therapy to be proposed is surgery, on its own or supported by pharmacoprosthesis.

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RESUMELe reflux veineux r(~no-spermatique est tr~s bien d~montr~ par I'~chographie couleur doppler (ECCD) et il est I'~lement h~modynamique de base de la varicoc~le. Nous avons essay~ de verifier I'utilit~ de la dissection, avec des lunettes chirurgicales permettant un grossissement de 4,5 des branches de la veine spermatique au niveau de I'orifice inguinal interne.16 patients ont ~te op(~r~s selon la classification ~chographique de Hirsh et al. [8]. La varicocele ~tait du Ille degr~ pour 2 cas, du IVe degre pour 11 cas et du Ve degre pour 3 cas. La varicoc~le ~tait gauche chez 13 patients et a droite dans 3 cas.Le diagnostic a ~t~ r~alis~ par examen clinique et ECCD. Le temps op~ratoire (~tait de 25.35 min. L'incision avait 1,5 b 2 cm de long. Nous n'avons jamais eu de complications b court terme, ni d'hydrocele b long terme. L'ECCD apr~s six mois n'a pas trouve de reflux r~no-spermatique. Le volume testiculaire moyen qui ~tait de 22 ml avant, ne changeait pas apres I'intervention chirurgicale.Cette intervention chirurgicale est moins invasive que I'intervention r~tro-p~ritoneale classique ou laparoscopique, et I'abord chirurgical est moins important respectivement b la technique percutan~e ; elle est moins radicale que I'intervention en microchirurgie classique, mais le temps op~ratoire est plus bref, et la plaie chirurgicale est plus petite ; elle respecte I'artere et les vaisseaux lymphatiques.En conclusion, cette intervention peut ~tre consid~r~e comme une bonne option dans le traitement chirurgical de la varicocble parce qu'elle a peu de complications, une absence d'hydroc~le, une importance chirurgicale limit~e et permet des bons r~sultats hemodynamiques. 9 varicocele, varicocelectomie, power-doppler, microchirurgie M o t s cl~s