3.0 (13:7:80 v/v/v)

This study aims to determine how to extract the gelatin from catfish bones by using pineapple peel waste as a soaking material in the pre-treatment stage and examining the physicochemical properties of the gelatin produced. Kampung Patin in Kampar Regency, Riau Province, is one of the catfish cultivations in Indonesia. It is a center for producing catfish that produces fish bone waste. In this study, gelatin extraction will be undertaken in several stages: the preparation of pineapple waste liquid extract and gelatin extraction (pre-treatment and main extraction stages). Catfish bones will be soaked in 1:5 (m/v) pineapple waste liquid at the pre-treatment stage for 24 hours. While in the central extraction, ossein will be immersed in water at a temperature of 750C for 5 hours. The analysis results for physicochemical characteristics of gelatin obtained include yield of 2.55, pH of 4.58, water content; 11.66%, ash content; 17.71%, crude fat content; 0.17%, protein content; 64.71%. It can be inferred that it meets the established gelatin quality standards from various physicochemical characteristics of gelatin in this study.

Nutrition education and the implementation of pregnancy exercises help mothers improve maternal health, prevent anemia and babies born with low weight. Maintaining the consumption pattern of pregnant women also prevents children from experiencing stunting. The purpose of this community service was to provide education and implementation of pregnancy exercise to improve the health status of pregnant women at the Sidomulyo Public Health Center, RI. The method used is the provision of health education and assessing the mother's understanding of nutrition and assessing the implementation of pregnancy exercise for pregnant women. The activity was carried out 3 times, starting with a pre-test and post-test related to knowledge of pregnant women and observing the implementation of pregnancy exercise. The number of pregnant women who participated in this activity was 9 people. The results showed that there was an increase in the average value of knowledge of pregnant women by 24.29. The results of the implementation of pregnancy exercise showed that 100% of pregnant women carried out pregnancy exercise in the good category. It is hoped that there will be an increase in the health status of pregnant women therefore that they do not experience anemia and normal birth weight babies and growth and development according to their age.   ABSTRAK Edukasi nutrisi dan pelaksanaan senam hamil membantu ibu meningkatkan derajat kesehatan, mencegah anemia dan bayi lahir dengan berat badan rendah. Pentingnya menjaga pola konsumsi ibu hamil juga mencegah anak mengalami stunting. Tujuan pengabdian masyarakat ini adalah pemberian edukasi dan pelaksanaan senam hamil untuk meningkatkan derajat kesehatan ibu hamil di Puskesmas Sidomulyo RI. Metode yang digunakan adalah pemberian pendidikan kesehatan dan menilai pemahaman ibu tentang nutrisi dan menilai pelaksanaan senam hamil pada ibu hamil. Pelaksanaan kegiatan sebanyak 3 kali dimulai dengan adanya pre–test dan post-test terkait pengetahuan ibu hamil dan observasi pelaksanaan senam hamil. Jumlah ibu hamil yang mengikuti kegiatan ini sebanyak 9 orang. Hasil didapatkan bahwa terdapat peningkatan nilai rata-rata pengetahuan ibu hamil sebesar 24,29. Hasil pelaksanaan senam hamil didapatkan bahwa 100% ibu hamil melaksanakan senam hamil pada kategori baik. Diharapkan adanya peningkatan derajat kesehatan ibu hamil sehingga tidak mengalami anemia dan berat badan bayi lahir normal serta pertumbuhan dan perkembangan sesuai dengan usianya.

Objective: This research aims to validate the method for rifampicin analysis in plasma by using High-Performance Liquid Chromatography (HPLC) that can be used to study the bioequivalence of a generic tablet of rifampicin 450 mg “X” marketed in Indonesia. Methods: Bioequivalence test was analysed using HPLC equipped with UV-Vis detector at 377 nm. The mobile phase used was acetonitrile-phosphate buffer pH 6.8 (45:55) delivered at a flow rate of 1.5 ml/min. Bioequivalence test was conducted on a limited number of subjects (n=8). The subjects were divided into two groups randomly. The pharmacokinetic profiles of the test tablet and reference tablet were statistically calculated using SPSS program to see the test tablet and reference tablet were bioequivalence or not. Results: The developed HPLC method for rifampicin analysis in plasma was sufficiently valid based on the International Conference on Harmonization (ICH) and European Medicines Agency (EMA) guideline, with precision and accuracy values were % Relative Standard Deviation (% RSD = 1.40–13.04) and % Recovery (86.24–102.13), respectively. Meanwhile, the method was linear over studied concentration (0.05 to 10.26 µg/ml) with a coefficient of determination (R2) = 0.9984. The method also had good stability and sensitivity. The result of statistical calculation showed that the generic rifampicin tablet X was bioequivalence toward the reference tablet Rimactan 450 mg. Conclusion: The test rifampicin tablet that was, the generic tablet “X” was bioequivalence toward the reference rifampicin tablet “Rimactan”.

One of health problems in Indonesia is stunting. Energy and nutrients intake are important factor in the occurrence of stunting conditions. The intake of micronutrients to prevent stunting are vitamin A, zinc, iron, iodine, and several other micronutrients such as calcium and phosphorus are also important in children’s linear growth. One of the plants which is a natural resource owned by Provinsi Riau and can be used as an alternative food to obtain calcium is Maman (Cleome gynandra L.). The analytical method used ultraviolet-visible spectrophotometry based on the complex formation between murexide and calcium. The optimum wavelength obtained is 530 nm with a r value = 0.9989. The LOD value obtained was 0.013 ppm and the calcium content in maman leaves was 172.64 ± 4.91 mg/g.