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Background: Autoimmune polyglandular syndrome (APS) is characterized by the coexistence of several autoimmune diseases, affecting predominantly the endocrine glands. APS type I is distinguished from type II in which autoimmune thyroiditis, Addison's disease and diabetes type 1 predominate. This article summarizes extensive epidemiological, clinical, and immunological data of a large population of Tunisian patients with APS II.

Abstract:The problem facing dairy cow producers in tropical area is the low availability of proper nutrition, especially during the dry season. One solution to overcome this problem is to utilize technology of Complete Feed (CF) silage using ensiled several local abundant ingredients from agricultural wastes. This study aimed to find a formulation of CF silage from agricultural wastes as forage substitution for dairy cows to increase yield and quality of the milk. The study was conducted on dairy farms in Enrekang District, South Sulawesi of Indonesia. The formulations of CF silage used in the study were tested both in vitro and in vivo and compared with the farmer's practices that using elephant grass plus rice bran. A total of 20 Holstein Friesian dairy cows in 4-5 months lactation with a lactation period of 3rd-5th were used for in vivo study. The treatments were Elephant Grass + Rice Bran (EG-RB), Elephant Grass + Concentrate (EG-CON), Complete Feed Silage made from straws (CF-S) and complete feed silage made from straws and vegetable wastes (CF-VW). The results of this study showed that the dry matter intake and milk yield of dairy cow were higher in EG-CON, CF-S and CF-VW compared to EG-RB and were not different among EG-CON, CF-S and CF-VW. The crude protein, lactose, calcium and phosphorus of the milk were higher in the EG-CON, CF-S and CF-VW than EG-RB and were not different among EG-CON, CF-S and CF-VW. Fat content, density and pH of the milk were not different among treatments. In conclusion, in order to maintain and to improve the yield and quality of milk in dairy cows, the agriculture wastes, such as straws and vegetable wastes can be used as the basal feed of dairy cows for fodder substitution in the form of CF silage.

The presence of oil seepage to the surface indicates that at least an active petroleum system is present subsurface. Oil seepage that occurred in Plantungan, Kendal, Central Java, has been known since 1971 and still produces seepage until today. On the research area, three oil seepages point were found. Plantungan region is located in East Serayu Zone underlain by volcanic area, and based on the Geology Map, the research area is located in Banjarnegara-Pekalongan Sheet. To understand the geology condition of the research area, a subsurface mapping is needed, even though the mapping does not provide the depth of bedrock and reservoir, data recording using HVSR (Horizontal to Vertical Spectrum Ratio) method that has been done in 18 points is able to provide Vp and density profile to understand the distribution of oil seepage. The oil seepage is most prominent close to SB09 location, however the result from crossplot found that the value of highest Vp×density is on SB12A with 4,306,197 kg/m2s, and lowest Vp×density in on SB17A with 302,305.3 kg/m2s.

Research about the synthesis of chitosan/alumina composite using the sol-gel method and its application to removal procion blue MX-R dye had been conducted. The synthesized chitosan/alumina composite was characterized using FTIR to determine functional group, SEM-EDS to find out the surface morphology and elements composition of chitosan/alumina composite. The pHPZC is used to determine the appropriate pH condition on the adsorption process of chitosan and chitosan/alumina composite on procion blue dye solution. The FTIR spectra of chitosan represent the functional groups O-H, N-H, C-H and C-O while the chitosan/alumina composite is the addition of functional group of Al-O. The morphology of chitosan/alumina composite analysis by SEM showed that is heterogenous and porous. The EDX analysis showed that the present Al element of 5.49 % in the composite which indicates that synthesis of composite has been successful. Chitosan and composite have different pH pzc where chitosan at pH 6.02 and composite at pH 7.26. The optimum condition adsorption of procion blue MX-R using chitosan obtained at an initial concentration of 180 mg/L and contact time of 60 minutes, while the chitosan/alumina composite obtained at an initial concentration of 160 mg/L and 50 minutes contact time. The isotherm model that is suitable for describing the adsorption process is Freundlich isotherm for both adsorbents. The composite has the effectiveness of adsorption on procion blue MX-R from wastewater songket industry greater than chitosan ie 85.696 and 60.829 %, respectively.