The present work studied the puncher-cutting accidents occurred among students, professors and employees of the College of Dentistry of the Federal University of Rio Grande do Sul. The dental instruments, the places affected, the condition of general health of the person involved in the puncher-cutting accidents and also the main circumstances were identified. The data analyzed were obtained from the Formulário de Acidente e Incidente de Serviço (FAIS), made by the college with the purpose of register the incidents. Twenty-five puncher-cutting accidents were reported between 2004 to 2006, with an average of 8, 33 cases per year. The moments of appointment of patients and manipulation of dental instruments were the most mentioned. The most related subjects or departments were Periodontics and Geriatric Dentistry. The most involved instruments were periodontal curettes and injection dental needles. In 24% of the cases the individuals did not use any kind of Individual Protection Equipment (IPE), in two cases were reported the lack of orientation for medical appointment or nursing. From the 21 students involved in the accidents, one had not made the vaccine against the Hepatitis B and 5 of them reported the absence of vaccination against the Tetanus. From the 25 cases studied only three of the patients said that they have transmitted diseases or pathogens. After study, found that institution needs improve their methods of biosafety control.

Osteoarthritis is a degenerative disease that causes substantial changes in joint tissues, such as cartilage degeneration and subchondral bone sclerosis. Chondroitin sulfate and glucosamine are commonly used products for the symptomatic treatment of osteoarthritis. The aim of the present study was to investigate the effects of these products when used as structure-modifying drugs on the progression of osteoarthritis in the rabbit temporomandibular joint. Thirty-six New Zealand rabbits were divided into 3 groups (n = 12/group): control (no disease); osteoarthritis (disease induction); and treatment (disease induction and administration of chondroitin sulfate and glucosamine). Osteoarthritis was induced by intra-articular injection of monosodium iodoacetate. Animals were killed at 30 and 90 days after initiation of therapy. The treatment was effective in reducing disease severity, with late effects and changes in the concentration of glycosaminoglycans in the articular disc. The results indicate that chondroitin sulfate and glucosamine may have a structure-modifying effect on the tissues of rabbit temporomandibular joints altered by osteoarthritis. OPEN ACCESSCitation: Artuzi FE, Puricelli E, Baraldi CE, Quevedo AS, Ponzoni D (2020) Reduction of osteoarthritis severity in the temporomandibular joint of rabbits treated with chondroitin sulfate and glucosamine. PLoS ONE 15(4): e0231734. https://doi.org/ 10.

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