The neural dysfunction is triggered by cellular and molecular events that provoke neurotoxicity and neural death. Currently, neurodegenerative diseases are increasingly common, and available treatments are focused on relieving symptoms. Based on the above, in this review we describe the participation of vitexin in the main events involved in the neurotoxicity and cell death process, as well as the use of vitexin as a therapeutic approach to suppress or attenuate neurodegenerative progress. Vitexin contributes to increasing neuroprotective factors and pathways and counteract the targets that induce neurodegeneration, such as redox imbalance, neuroinflammation, abnormal protein aggregation, and reduction of cognitive and/or motor impairment. The results obtained provide substantial evidence to support the scientific exploration of vitexin in these pathologies, since their effects are still little explored for this direction.

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A dengue transmitida pelo mosquito Aedes aegypti é controlada por larvicida, inseticida e repelente. Os óleos essenciais à base de plantas são usados como excelentes repelentes. Portanto, a presente revisão é essencial para o entendimento da eficácia dos óleos essenciais contra os mosquitos. Os artigos relacionados a óleos essenciais foram pesquisados de 2014 a 2022 no Pubmed, Science Direct, LILACS, Scielo e Google Scholar usando as seguintes palavras-chave: óleo essencial, Aedes aegypti e repelentes. Um total de 280 plantas foram extraídas para EOs de 33 famílias. A maioria das plantas pertence a Lamiaceae (45,4%), seguida por Myrtaceae (38,3%) e Rutaceae (28,4%). Os metabólitos em OE com atividade repelente / larvicida máxima incluem β-cariofileno, α-pineno, 1,8-cineol, linalol e eugenol, as concentrações letais variaram de 40 a 120 ppm. Esses resultados apóiam a visão de que os óleos essenciais são promissores na formulação de repelentes, larvicidas, inseticidas e pesticidas.

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