Pendahuluan: Peradangan merupakan respon dasar terhadap adanya kerusakan jaringan atau luka pasca pencabutan gigi yang kemudian dilanjutkan dengan proses penyembuhan. Lendir bekicot dari spesies Achatina fulica diketahui memiliki kemampuan sebagai alternatif obat yang mempercepat proses penyembuhan luka. Tujuan Penelitian: penelitian ini bertujuan menguji pengaruh lendir bekicot (Achatina fulica) terhadap jumlah limfosit pada proses penyembuhan luka soket gigi pasca pencabutan gigi tikus wistar (Rattus norvegicus). Bahan dan Metode: Penelitian ini menggunakan bahan utama berupa lendir bekicot  yang diaplikasikan pada soket gigi tikus. Sampel dipilih menggunakan teknik Simple Random Sampling kemudian dibagi ke dalam dua kelompok, yaitu kelompok kontrol (K) dan perlakuan (P). Variabel yang diteliti pada penelitian ini adalah jumlah limfosit pada hari ketiga, kelima, dan ketujuh proses penyembuhan luka soket gigi tikus wistar yang diukur dari sediaan HPA dengan pengecatan Hematoxylin-Eosin. Hasil: Hasil penelitian menunjukan adanya perbedaan jumlah limfosit pada hari ketiga, kelima, dan ketujuh baik pada kelompok kontrol (K) maupun perlakuan (P). Dengan jumlah rerata limfosit pada kelompok kontrol adalah 5,48 ; 4,60 ; 64,48. Sedangkan hasil rerata limfosit kelompok perlakuan adalah : 11,6; 16,52; 10,80. Kesimpulan : penelitian ini menunjukkan bahwa lendir bekicot (Achatina fulica) berpengaruh pada jumlah limfosit pada proses penyembuhan luka soket gigi tikus wistar (Rattus norvegicus).

Tooth extraction is a common treatment in dental practice. However, complications such as bleeding or dry socket may occur during healing process. Pangas catfish (Pangasius djambal) gelatin contains glutamine which could increase the proliferation of fibroblast, accordingly collagen synthesis increases. The study aimed to demonstrate collagen density after the application of pangas catfish gelatin on post-tooth extraction wound of albino rats (Rattus norvegicus). This wasan experimental study with randomized posttest-only control group design which involved male Wistar strain albino rats. The rats were selected using a random sampling method and divided into four groups, namely day-3 control group (n=7),day-7 control group (n=7), day-3 treatment group (n=7) and day-7 treatment group (n=7). Pangas catfish gelatin was administered into the socket once after extraction. The variable measured in the study was collagen density, determinedby collagen scoring of hematoxylin eosin–stained histopathological preparations. Collagen formation were determined according to the assessment criteria of collagen distribution and density. Data analysis showed there was a significantdifference of collagen synthesis between the control and treatment groups according to Kruskal-Wallis test of which the result of control group day-3 was 1.13 ± 0.34, control group day-7 was 1.76 ± 0.67, treatment group day-3 was 1.66 ±0.47 and treatment group day-7 was 2.93 ± 0.25. In addition, the day-7 treatment group showed the highest collagen scoring values as compared to the control groups according to the Mann-Whitney test (p<0.05). In conclusion, pangascatfish gelatin increased collagen density during dental socket healing process after tooth extraction in albino rats.

Background: Gelatin has been used as a hemostatic agent to stop bleeding and it can be absorbed by human body within 6 hours. The patin fish (Pangasius djambal) gelatin has a high amount of amino acid, especially glutamine which has an important role in increasing the proliferation of fibroblast in wounds. The purpose of this study was to determine the effect of patin fish gelatin to the number of fibroblast in wound after tooth extraction.Method: Rat’s tooth extraction is done on the lower left incisive tooth. Thirty white rats were divided into two groups randomly with 3 time series. Control group was the rats without given of patin fish gelatin and treatment group was the rats given 1cc of patin fish gelatin with pipette. Socket taken for histologically processed by Hematoxylin Eosin staining.Result: It showed there were significant differences in the number of fibroblasts between groups. The Post Hoc Tukey test result showed there was a significant difference between the control group and the treatment group.Conclusion: Patin fish gelatin has effect increasing the number of fibroblast inwound after white rat’s (Rattus norvegicus) tooth extraction

Background: Tooth loss has serious functional, esthetic disabilities, and compromising the patients' quality of life. Dental implant treatment has become increasingly common for the management tooth loss. Different clinical situations, such as narrow edentulous space, are often encountered in which modifications have to be considered in order to achieve successful rehabilitation. One piece dental implan provided a solution for rehabilitation of narrow edentulous space. The purpose of this paper is to report a rehabilitation management of narrow edentulous space. Case Management: A 22-year-old woman had an upper right canine #13 malposition so there was a narrow space between upper right lateral insisiv #12 and upper right first premolar #14. The spacing between upper right lateral insisivus #12 and upper right first premolar #14 was found to be about 5 mm. Radiograph was assessed for type of bone and for the presence of any pathology.

Inflammation is a phase of the wound healing process that occurs after tooth extraction which is influenced by the immune system. Lymphocytes are one type of cell in the immune system that have an important role in the inflammation process. The purpose of this study was to investigate the effect of Pangasius djambal gelatin treatment on the enhancing lymphocyte cell count after tooth extraction in Rattus norvegicus. In this study, the in vivo true experimental laboratories with a post-test group design was maintained. In this study, we performed 3 control groups without treatment by the Pangasius djambal gelatin and 3 treatment groups with 100 mg/mL Pangasius djambal gelatin on the post-extraction wound of the mandibular left lateral incisor of Rattus norvegicus. Each group consists of 5 rats. The lymphocyte cells count in the tooth socket tissue was evaluated on days 3, 5, and 7. The control groups' lymphocyte cells count decreased significantly from 32 to 17.2 from day 3 to day 7. Interestingly, the lymphocyte cells of treatment groups increased from 92.2 to 114.6 from day 3 to day 7. Furthermore, a very strong positive correlation between the observation time and lymphocyte cell count was observed in this work (r = 0.838; very strong). Therefore, the Pangasius djambal gelatin opens new potency to increase the lymphocyte cells count after tooth extraction. Keywords: Pangasius djambal fish, Lymphocytes, Tooth extraction, Intraperitoneal anesthesia