Four experiments were conducted to determine the standardized ileal digestible (SID) Lys requirement of pigs (Sus scrofa) from 7 to 14 kg. In Exp. 1, 294 pigs (6.8 kg BW) were used in a 28-d growth trial with 7 pigs per pen and 7 pens per treatment. Treatment diets were fed from d 0 to 14, and a common diet was fed from d 14 to 28. The 6 SID Lys levels tested were 1.15, 1.23, 1.30, 1.38, 1.45, and 1.53%. The diets were corn- and soybean-meal [Zea mays L. and Glycine max (L.) Merr.] based, with 10% spray-dried whey, 4.5% fish meal, and contained 3.37 Mcal of ME/kg. From d 0 to 14, ADG increased (quadratic, P < 0.001) as SID Lys increased from 1.15 to 1.30% with no further increase at greater levels. Gain:feed increased (linear, P < 0.001) with increasing SID Lys. Experiments 2 to 4 were 14-d growth trials with diets containing 1.22, 1.32, 1.42, 1.52, or 1.62% SID Lys. Diets were corn- and soybean-meal based with 3.45 Mcal of ME/kg. Soybean meal and lactose were constant in all diets at 30 and 7% of the diet, respectively. In Exp. 2, 840 pigs (7.6 kg BW) were used, with 24 pigs per pen and 7 pens per treatment. Increasing SID Lys from 1.22 to 1.42% increased (quadratic, P < 0.01) ADG and G:F with no further improvement observed in pigs fed the 1.52 or 1.62% SID Lys diets during d 0 to 14. In Exp. 3, 1,260 pigs (8.5 kg BW) were used with 42 pigs per feeder (2 pens per feeder) and 6 feeders per treatment. Increasing dietary Lys increased (quadratic, P < 0.02) ADG and G:F with the greatest response observed as SID Lys increased from 1.22 to 1.32% and, then, slight improvements with 1.42 and 1.52% during d 0 to 14. In Exp. 4, 770 pigs (7.4 kg BW) were used with 22 pigs per pen and 7 pens per treatment. Increasing SID Lys increased (quadratic, P = 0.05) ADG with pigs fed 1.32 and 1.42% SID Lys diets having the greatest BW gains during d 0 to 14. Increased SID Lys decreased (linear, P < 0.001) ADFI and increased (linear, P < 0.001; quadratic, P = 0.02) G:F. In conclusion, results of these experiments indicate that the 1998 NRC Lys recommendations (e.g., 1.19% SID Lys for 5 to 10 kg pigs) are less than required for optimal growth for 7 to 14 kg pigs. One-slope straight broken-line analysis indicated that the SID Lys requirement for optimal growth was at least 1.30% for ADG and 1.37% for G:F, or at least 3.86 and 4.18 g SID Lys/Mcal ME, respectively. Quadratic broken-line analysis indicated that the SID Lys requirement for optimal growth was at least 1.37% for ADG and 1.54% for G:F, or at least 4.19 and 4.92 g SID Lys/Mcal ME, respectively.
The objectives of this experiment were to evaluate the effects of alternatives to antibiotic growth promoters (AGP), two group sizes, and their interaction on nursery pig performance to serve as a model for future AGP alternative studies. A 41-d experiment was conducted in a commercial wean-to-finish barn; 1,300 piglets weaned at 21 d of age (weaned 2 or 4 d prior to experiment; 6.14 ± 0.18 kg BW; PIC 1050 sows and multiple sire lines) were blocked by sire, sex, and weaning date, then assigned to eight treatments: four dietary treatments each evaluated across two group sizes. The four dietary treatments were: negative control (NC), positive control (PC; NC + in-feed antibiotics), zinc oxide plus a dietary acidifier (blend of fumaric, citric, lactic, and phosphoric acid) (ZA; NC + ZnO + acid), and a Bacillus-based direct-fed-microbial (DFM) plus resistant potato starch (RS) (DR; NC + DFM + RS). The two group sizes were 31 or 11 pigs/pen; floor space was modified so area/pig was equal between the group sizes (0.42 m2/pig). There were 7 pens/diet with 11 pigs/pen and 8 pens/diet with 31 pigs/pen. Data were analyzed as a randomized complete block design with pen as the experimental unit. Diagnostic assessment of oral fluids, serum, and tissue samples was used to characterize health status. Pigs experienced natural challenges of acute diarrhea and septicemia in week 1 and porcine reproductive and respiratory syndrome virus (PRRSV) in weeks 4–6. There was a significant interaction between diet and group size for ADG (P = 0.012). PC increased ADG in large and small groups (P < 0.05) and ZA increased ADG only in large groups (P < 0.05). Small groups had improved ADG compared to large groups when fed NC or DR diets (P < 0.05). Similarly, PC increased ADFI (P < 0.05). Compared to NC, ZA improved ADFI in large groups only (P < 0.05; diet × group size: P = 0.015). Pigs fed PC had greater G:F than NC (P < 0.05), and small groups had greater G:F than large groups (P < 0.05). There was no effect of ZA or DR on G:F. Pigs fed PC required fewer individual medical treatments than NC and pigs fed ZA were intermediate (P = 0.024). More pigs were removed from large than small groups (P = 0.049), and there was no effect of diet on removals (P > 0.10). In conclusion, careful study design, protocol implementation, sample collection, and recording of important information allowed us to characterize the health status of this group of pigs and determine treatment effects on growth performance and morbidity.
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