It can be concluded that the extracts of C. erythrophyllum are safe for medicinal use in folk medicine for treating infectious and stress related diseases.

In this study, we aimed to profile the stem bark of Acacia decurrens biochemically. Extracts obtained by maceration were phytochemically screened, spectroscopically analysed with the aid of UV-visible, FT-IR, GC-MS, and, ICP-OES and subjected to primary biological assay. Spectra obtained from the UV-visible and FT-IR confirm the presence of n ® p*  which are characteristic of compounds with oxygenated backbones such as the glycoside, phenols, terpenoids, tannins, and flavonoids. On further analysis, the chromatogram revealed the presence of thirty-five major compounds of which eight bioactive compounds had previously been isolated. The metal profile of the stem bark registered high concentrations of Cr, K, and Fe. Quantitative phytochemical evaluation showed, large amount of tannins (30.87 – 55. 81 mgTAE/g), steroids (13.92-41.2%), and phenols (40.6 - 65.5 mgGAE/g) in all fractions. The ethyl acetate and methanol fractions were found to be rich sources of antibacterial compounds with MIC value of 12.5 μg/mL while the chloroform fraction is a potent antioxidant fraction with IC50 values of 37.00 ± 0.06 g/mL and 42.20 ± 0.72 µg/mL against DPPH and ABTS radicals, respectively. The presence of these secondary metabolites and the hyper-tolerance capacity for metals can be exploited pharmaceutically and for phytoremediation purpose, respectively.

Herbal medicine is a form of medicine that has been extensively exploited in traditional medicine, and its therapeutic potential is accepted. Combretum is one of the most frequently happening genera in the African and Asia tropical and subtropical areas; some are widely used in African herbal medicine due to their ethnopharmacological properties. Numerous species of this plant have been used and expended owing to high pharmaco-constituents following their phytochemical screening and evaluations. The recent incidence of multidrug-resistant strains and reduced receptiveness to antibiotics has raised serious anxiety in health delivery and the need for an urgent search for new antibiotics mediators from nature. A countless number of natural substances have resulted from the Combretum species as medicine and are utilized traditionally for the management of bacteriological infection. The plants have received comprehensive documentation as a good cradle of natural constituents that can be categorized into four groups following their biosynthetic source: alkaloids, terpenoids, polyketides, and phenylpropanoids. The study deals with the ethnobotanical and pharmacological significance of the Combretum species for treating numerous ailments and diseases.