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Twenty three kojic acid derivatives were tested in the agar diffusion test against twenty five dermatophytic fungi. The inhibitory effects at equal doses (10 mg/L) were correlated with the 1-octanol-water partition coefficients of the compounds. An improvement in antifungal activity can be achieved by increasing the hydrophobicity of the compounds.

Derivatives of 4H-Pyran-4-one with the Atom of Sulfur in the Side Chain.-[synthesis and biological evaluation of sulfur-containing derivatives of kojic acid such as (III), (IV), and (VIII)]. -(UHER, M.; KYSELICOVA, L.; RAJNIAKOVA, O.; HUDECOVA, D.; BRANSOVA, J.; BRTKO, J.; Chem.