ObjectiveTo compare oral health parameters in perinatally HIV-infected (PHIV) and perinatally HIV-exposed but uninfected youth (PHEU).MethodsIn a cross-sectional substudy within the Pediatric HIV/AIDS Cohort Study, participants were examined for number of decayed teeth (DT), Decayed, Missing, and Filled Teeth (DMFT), oral mucosal disease, and periodontal disease (PD). Covariates for oral health parameters were examined using zero-inflated negative binomial regression and ordinal logistic regression models.ResultsEleven sites enrolled 209 PHIV and 126 PHEU. Higher DT scores were observed in participants who were PHIV [Adjusted Mean Ratio (aMR) = 1.7 (95% CI 1.2–2.5)], female [aMR = 1.4 (1.0–1.9)], had no source of regular dental care [aMR = 2.3 (1.5–3.4)], and had a high frequency of meals/snacks [≥5 /day vs 0–3, aMR = 1.9 (1.1–3.1)] and juice/soda [≥5 /day vs 0–3, aMR = 1.6 (1.1–2.4)]. Higher DMFT scores were observed in participants who were older [≥19, aMR = 1.9 (1.2–2.9)], had biological parent as caregiver [aMR = 1.2 (1.0–1.3)], had a high frequency of juice/soda [≥5 /day vs 0–3, aMR = 1.4 (1.1–1.7)] and a low saliva flow rate [mL/min, aMR = 0.8 per unit higher (0.6–1.0)]. Eighty percent had PD; no differences were seen by HIV status using the patient-based classifications of health, gingivitis or mild, moderate, or severe periodontitis. No associations were observed of CD4 count and viral load with oral health outcomes after adjustment.ConclusionsOral health was poor in PHIV and PHEU youth. This was dismaying since most HIV infected children in the U.S. are carefully followed at medical health care clinics. This data underscore the need for regular dental care. As PHIV youth were at higher risk for cavities, it will be important to better understand this relationship in order to develop targeted interventions.
Millar Western Forest Products Ltd. manages a forest in west-central Alberta under a Forest Management Agreement (FMA) with the Government of Alberta. Part of Millar Western's planning process brought researchers together to develop a decision support system (DSS) for forest management planning and monitoring programs. Four modules timber supply, biodiversity, FIRE, and WATER were built to evaluate, with the help of indicators of sustainable forest management, current and future forest conditions predicted from computer simulations of alternative management scenarios. In the first round of assessment four management scenarios, distinct by their level of silviculture intensification and by the spatial clearcut layout pattern, were compared. Such comparison has demonstrated that (1) the current forest management scenario improved moose habitat at the expense of timber supply, (2) all scenarios had similar fire risk, (3) generated increases in peak flow and water yield of selected watersheds, and (4) slightly impoverished forest biodiversity. All scenarios were examined in light of a computer-simulated natural disturbance benchmark. This led to landscape design scenarios to reduce fire risk and balance biodiversity indicators with timber supply objectives, one of which was eventually selected for implementation. The company's monitoring and research program is also highly focused on improving DSS modules and the underlying data, hence its association with the Forest Watershed and Riparian Disturbance (FORWARD) project, which considers the effects of forest management on aquatic ecosystem indicators. Key words: decision support system, ecosystem management, forest management, natural disturbance, indicators, sustainable forest management, adaptive management.
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