The increasing chemicalization of production and life leads to the pollution of water bodies by chemicals, the effect of which on the micro - and macro - organisms is poorly understood. This section of the study in sanitary bacteriology is becoming ever more topical and is an important task of modern hygienic science. One of complicacies of the study of the problem is related with the fact that the presence of only experimental data fails to be sufficient, as the impact of any given chemical substance on different bacteria in the experiment does not mean that under natural conditions, similar results will be obtained. One reason for this may be the inhibitory effect of the given chemical on biological properties of bacteria, while in field conditions in the water several chemicals interacting with each other can exist. In this regard, the aim of the work was to assess the indicator value of sanitary and microbiological indices of epidemic hazard of water use in conditions of chemical pollution of surface water bodies.

Introduction. The high level of trade, population migration, and changes in the infrastructure of economic activity in the regions created the prerequisites for the dispersal and adaptation of parasitic pathogens to new factors, including adverse environmental and climatic conditions of their circulation. For the first time on the example of the distribution of long-term average incidence rates among the four most common parasitic nosological forms, the etiological factor of which is the causative agents of different taxonomic groups, systematized by the type of their circulation in various environmental objects: ascariasis (soil), enterobiosis (household items), opisthorchiasis (fish, products processing), echinococcosis (soil, water, contact with sick animals, processed products of animal raw materials. At the same time, a high level of soil contamination resistance (42.1%), surface runoff (41.8%), surface water (42.5%), sewage sludge (35.1%) characterizes the resistance of the parasitic system to the effects of the existing anthropogenic press on the causative agents of helminth and protozoal infestations and indicates the maintenance of active circulation of pathogens in the environment. Material and methods. The analysis of the average long-term level of parasitic morbidity and changes in the boundaries of the territorial distribution of parasitoses over the past 10 years (2009-2018) in 85 administrative units of the Russian Federation. The epidemiological development trend is determined by the methods of ranking the dynamic series of incidence with categorization by levels relative to the average Russian indices of parasitic incidence and calculation of the linear trend. Results. The calculation data are plotted on the administrative-territorial map of Russia with the help of a GIS program (MapInfo Pro 16) with the allocation of SMPZ levels for each nosology - single, low, medium, high, super high. Conclusion. Calculations of the development of linear trends of medium and low levels, as well as single cases of morbidity, were shown to allow differentiating the development trend of the epidemic process and draw prognostic conclusions.

There were identified priority pollutants in water of the Moscow river below the city (petroleum products, lead, cadmium, zinc, copper; anionic surfactants), which can affect the natural microbiocenosis of surface water. The presence in surface waters heavy metals - cadmium in a concentration of 4 MPC for fishery purposes, of lead at a concentration of 5 MPC for fishery purposes, oil at a concentration of 49 MPC, zinc at a concentration of 10 MPC for fishery purposes, anionic surfactants at the concentrations below the MPC, and also at excess of MPC by 5 times for chlorides, nitrites and nitrates to a large extent was established to affect the viability of indicator bacteria - coliforms, E. coli, enterococci, while maintaining in the water of pathogenic bacteria - Salmonella and parasitic pathogens living Entamoebae spp. and cystic viable vegetative forms of pathogenic protozoa Flagellata spp. and viable helminth eggs Larvae spp.

Федеральное государственное бюджетное образовательное учреждение высшего образования «Московский государственный университет технологий и управления им. К.Г. Разумовского (Первый казачий университет)», 109004, г. Москва, Российская Федерация 2 Федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет), 119991, г. Москва, Российская Федерация 3 Федеральное государственное бюджетное учреждение «Центр стратегического планирования и управления медико-биологическими рисками здоровью» Федерального медико-биологического агентства России,

The article highlights the main problems of parasite monitoring in the Russian Federation and reveals a number of important tasks that need to be addressed in the coming years. To carry out qualitative monitoring of parasites in Russia, statistical data should be informative and reliable, only it will contribute to the solution of the tasks.