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Funding informationScience Achievement Scholarship of Thailand (SAST); Mae Fah Luang University (MFU) Copper(II) (Cu 2+ ) ion-imprinted polymers were prepared by suspension polymerization using 2.5 mmol of copper(II) sulfate pentahydrate as the template ion, 5 mmol of 4-vinylpyridine and methacrylic acid as functional monomers, 20 mmol of ethylene glycol dimethacrylate as the cross-linker, 1 mmol of 1,1′-azobis (cyclohexanecarbonitrile) as the initiator in the porogen of 10 mL of toluene, and hydroxypropyl methyl cellulose as a stabilizer in the polymerization reaction. The obtained polymers were used to quantify Cu 2+ ion by using flame atomic absorption spectroscopy. Chemical structure, morphology, crystalline structure, and surface area of polymers were investigated by Fourier transform infrared spectroscopy, scanning electron microscope, X-ray diffraction, and Brunauer-Emmett-Teller respectively. The diameters of the synthesized polymer particles were about 250 nm. The Cu 2+ ion-imprinted polymers illustrated good recognition property and selective adsorption ability with Cu 2+ higher than Mn 2+ and Fe 2+ . Thus, this work could be applied as a sorbent from the enrichment of Cu 2+ ions in analytes.

The prednisolone molecularly imprinted polymer nanoparticles (prednisolone-MIPs) were prepared via precipitation polymerization. The synthetic conditions were performed by optimizing of functional monomers (acrylamide and methacrylic acid) and crosslinkers (ethylene glycol dimethacrylate and pentaerythritol triacrylate) with defined the synthetic ratio of template molecule:functional monomer:crosslinker as 1:7:30. The acquired MIPs were studied for their binding quantitation by kinetic adsorption analysis. Two of four synthetic conditions reached an equilibrium binding capacity at 960 minutes. In addition, the equilibrium adsorption, kinetic models, adsorption isotherms, and molecular selectivity were also evaluated in this study.The pseudo-second order was the best fitted kinetic model with good agreement on Langmuir isotherm of both optimum conditions. The molecular recognition of prednisolone-MIPs was further carried out to demonstrate the selectivity performance and found that prednisolone-MIPs had a good recognition to target prednisolone rather than structural analogue.

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