The success rate of tracheal intubation using the Pentax-AWS was high in patients with difficult laryngoscopy with a Macintosh laryngoscope and in patients with predicted difficult intubation.
Clinicians should consider postponing primary plastic surgery for cleft lip and palate in infants with a suspected presence of a common cold. Our results also suggest that the presence of a wide cleft is a risk factor for causing perioperative respiratory complications in infants with cleft lip and palate. We believe that a careful preoperative assessment of common cold symptoms in these infants can decrease the incidence of perioperative respiratory complications.
: The ryanodine receptor (RyR) is an intracellular calcium ion (Ca2+ ) release channel. The C-terminal region of RyR was proposed to contain the transmembrane segments that form the channel into the endoplasmic reticulum (ER) while the large N-terminus, termed the "foot", was thought to be the cytoplasmic region of the protein. In order to confirm this proposed structure of RyR 1, we have generated RyR 1 mutants that were serially deleted from the 3' to the 5' terminal which were tagged to enhanced green fluorescent protein (EGFP) in Chinese hamster ovary (CHO) cells. The C-terminal deleted clones which lacked a putative transmembrane region and a small N-terminal portion which was further deleted to the N-terminal Thr184 were retained in the cytoplasmic region even after being permeablized by absolute methanol, the same as full-length RyR 1. These results suggest that there are also sequences for ER retention within the N-terminal region (between Met 1 to Thr 184) of RyRI.
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