Background: Neurological disorders is becoming a growing concern both for developed and developing countries. Magnitude of the problem is increasing day by day. Among all neurological disorders, stroke is the leading cause of morbidity and mortality globally.Objectives: The purpose of the study was to see the trend of admission of patients with neurological diseases and to study the outcome of patients at referral neurology hospital in Bangladesh.Methodology: This retrospective chart review was conducted in the blue unit of the Department of Neurology at National Institute of Neurosciences and Hospital, Dhaka, Bangladesh from 1st January to 31st December 2016 for a period of one (01) year. All the admitted patients with both sexes were selected as study population. The outcome was observed among the study population.Result: A total number of 1044 patients were admitted during the study period. Majority of the patients were in the age group of the 41 to 50 years which was 417(39.9%) cases. Both male and female were in highest number in the month of May which was 63 and 48 cases respectively. The total death of the study population was 146(14.0%) cases. The mean length of hospital stay was 8.4±2.31 days.Conclusion: Middle aged male is the main bulk of the neurological patients, admitted in a referral neurology hospital in Bangladesh. Highest admission and mortality was observed in stroke patients.Journal of National Institute of Neurosciences Bangladesh, 2018;4(2): 69-74

Abstract:Based on the fact that urinary hypocalciuria in pre-eclampsia this study was designed to determine the predictive value of calcium to creatinine ratio in a spot urine sample in second trimester of pregnancy. The calcium to creatinine ratio Calcium/creatinine ratio has been considered for early detection of pre-eclamptic toxaemia (PET) Keywords: Pre-eclampsia, calcium/creatinine ratio Introduction: Pre-eclampsia (PET) is one of the fatal complication of pregnancy. It is a pregnancy induced auto-intoxication with multi-system disorder of unknown etiology which is associated with triad of oedema, hypertension and proteinuria occurs mostly in nullipara after 20th week of gestation and most frequently near term. 1,2 Early test for prediction of PET previously reported are platelet count,hematocrit,serum uric acid and microalbuminuria are poor predictor of PET. Fibrinectin, urinary calcium excretion, roll over test, Doppler ultrasound showed contradictory and non-conclusive. Isometric exercise test showed predictive value but only two studies performed. Angiotensin II sensitivity test best predictive value but clinically not practiced. There is no test that fulfils all criteria established to be a good predictor of PET. 3 It has been found that increased urinary albumin and decreased calcium excretion may be an early marker for pre-peclampsia. 4 Urinary calcium/creatinine ratio less than or equal to 0.04 which may be an early marker for useful screening tool in predicting the subsequent development of pre-eclampsia. 5 So determination of calcium/creatinine ratio may easily predict the case of PET because previously it was reported that 24 hrs. urine samples can be replaced by a single voided urine. 6,7,8,9 But no data is available on this aspect in our country. Therefore this study was conducted to determine the relationship between PET, hypocalciurea and calcium to creatinine ratio for early prediction of PET in a spot urine sample. Materials And Methods:This is a non-interventional perspective cross sectional study that was approved by the institutional thesis review board of Rajshahi Medical College and it was also carried out on total number of 60 women with age ranged from 17-39 years of the m 30 normotensive gravid women and 30 suspected PET women were taken as study population. All the subjects were selected from department of obstetrics and gynecology, outdoor and indoor, Rajshahi Medical College Hospital. A complete obstetrical history, clinical examination and necessary investigations were done to exclude other conditions affecting urinary calcium/creatinine ratio. All the subjects were taken from middle and lower middle socioeconomic classes. Urinary calcium, urinary creatinine and urinary calcium/creatinine ratio were determined by using reagent kits Human and Tradesworth Germany. Calcium was measured by o-cresolpthelein complexions method & creatinine was measured by alkaline picrate method of Jaffe 10,11 in the department of Pharmacology, Rajshahi Medical College, Rajshahi. The signific...

Relapsing polychondritis is a rare, severe, episodic and progressive inflammatory disorder of unknown aetiology and autoimmune pathogenesis, causing recurrent inflammation of involving cartilaginous structures, predominantly those of the ears, nose, and laryngotracheobronchial tree. Rarity of this disease, array of many possible presenting symptoms, lack of specific diagnostic investigation and episodic nature often causes significant delay in diagnosis. We are reporting a 55 year old woman presenting with recurrent episodes of pain, swelling, redness of nose, and both ear resulting in depressed nasal bridge and floppy pinna. Relapsing polychondritis was diagnosed and she was treated with systemic corticosteroid successfully.DOI: http://dx.doi.org/10.3329/jom.v15i1.19881 J Medicine 2014; 15: 80-83

Case Report22 years of age normotensive, nondiabetic women admitted at department of Medicine, Dhaka Medical College Hospital with the complaints of fever, multiple joint pain and skin rashes over whole body for last 3 months. Fever was high grade continuous in nature. Generalized macular rashes especially in upper limbs, chest and back, with symmetrical polyarthritis involving wrist, proximal interphalangeal joints (PIP), metacarpophalangeal joints (MCP), knees and ankles. On quarry she also gave no history of sore throat for last 1 month. There were no early morning stiffness, ocular symptoms, orogenital ulcers, urinary symptoms, photophobia, and contact to infected person or major systemic symptoms.

Background: In evaluation of non-traumatic subarachnoid hemorrhage CT angiography (CTA) has 97-98% sensitivity and near 100% specificity. Objective: This study was conducted to evaluate the CTA findings of CT positive non traumatic subarachnoid hemorrhage. Methodology: This is an observational cross sectional study performed in Neurology department of National Institute of Neurosciences and Hospital, Dhaka over one year period (January 2019 to December 2019). Total 87 CT positive subarachnoid hemorrhage cases were purposively included in this study. All CT positive patients underwent CTA of Cerebral vessels for further evaluation. The angiography were evaluated by competent neuro-radiologists blinded about the study. Result: Among 87 patients, 40.2% were male and 59.8% were female. The average age was 53.33±11.1 years. Among the studied patient the source of bleeding was found 78.16% aneurysmal and 21.84% non-aneurysmal. 85.30% patients had single aneurysm and 14.70% had multiple aneurysm. The highest number of patient had Acom aneurysm (41.17%) followed by MCA (22.05%), ICA (13.23%), ACA (7.35%) and vertebral artery (1.14%) in order of frequency. Among the multiple aneurysm group most of the patients had combination of Acom, MCA and ICA aneurysm. Conclusion: From this study, we can conclude that CTA can be used as the primary diagnostic tool in evaluation of spontaneous SAH. Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 78-81