We theoretically predict a generation of a current in Weyl semimetals by applying circularly polarized light. The electric field of the light can drive an effective magnetic field of order of ten Tesla. For lower frequency light, a non-equilibrium spin distribution is formed near the Fermi surface. Due to the spin-momentum locking, a giant electric current proportional to the effective magnetic field is induced. On the other hand, higher frequency light realizes a quasi-static Floquet state with no induced electric current. We discuss relevant materials and estimate order of magnitude of the induced current.

We theoretically study the circularly polarized light-induced Floquet state in line-node semimetals with time-reversal symmetry and inversion symmetry. It is found that the Floquet state can show the photovoltaic anomalous Hall effect when an applied circularly polarized light gaps out the line node in the bulk and leave Weyl point nodes. The Hall conductivity is sensitive to the location of Fermi level: When the Fermi level locates at the node, the Hall conductivity depends on the radius of line node and is nearly independent of the intensity of light. Away from the line node, the Hall conductivity is dependent on the intensity of light. Such a sensitive Fermi-level dependence of the Hall conductivity in the presence of a weak laser intensity can have applications in phototransistors based on thin films of line-node semimetals.

Primary malignant melanoma of the esophagus is a very rare and deadly disease, with a survival of 2.2% at 5 years and a median survival of about 10 months. The aggressive biological behavior of this disease and advanced stage at the time of diagnosis together with the lack of effective treatment have contributed to its poor prognosis. We present the case of a 45-year-old Japanese man diagnosed as having a primary melanoma of the esophagus by clinical evaluation and a histological examination of endoscopic biopsy specimens. A novel approach consisting of pre- and post-operative chemo-hormone therapy with dacarbazine, nimustine, cisplatin and tamoxifen in conjunction with radical esophagectomy accompanied by lymph node dissection was carried out. The tumor size was decreased to 70% by the pre-operative chemo-hormone therapy. During the post-operative 32 months of follow-up, no evidence of recurrence or metastatic disease has been found. Although this is only one case, the outcome observed suggests that the combination of pre- and post-operative chemo-hormone therapy and radical esophagectomy with lymph node dissection is a modality that can increase the possibility of curability or at least improve the survival of patients with primary melanoma of the esophagus.

The thermal damage threshold of normal brain tissue was evaluated from immediate and delayed histological changes caused by hyperthermia treatment of normal monkey (Macaca fuscata) brains. A 2450 MHz microwave antenna and an antenna cooling system devised by our group were used for in terstitial hyperthermia treatment. The antenna within the cooling system was inserted through a small craniectomy under general anesthesia. The temperature at a reference point, 4 mm radially away from the surface of the cooling system, was maintained at 42, 43, 44, 45, or 46°C for 60 minutes. Eighteen animals were treated and sacrificed immediately after the treatment, while nine animals were treated and sacrificed 7 days after the treatment. The histological changes were studied microscopically on sec tions stained with HE or Kluver-Barrera's method. The non-survival experiment demonstrated that areas heated at 44°C or below showed no obvious irreversible changes. The survival experiment showed areas heated at 44°C or above developed coagulative necrosis. These histological findings in dicate that thermal damage occurs in normal brain tissue after heating at 44°C or above for 60 minutes, suggesting that the safety limit for brain hyperthermia is 43°C for 60 minutes.