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El presente artículo reflexiona sobre unaexperiencia de articulación de niveles llevada a cabo enel marco del Proyecto Nexos, aprobado por la Secretaríade Políticas Universitarias del Ministerio de Educación yDeportes de la Nación, e implementado por la Direcciónde Articulación e Ingreso, dependiente de la Secretaríade Planeamiento Institucional y Académico de la UniversidadNacional del Litoral; y el Ministerio de Educaciónde la Provincia de Santa Fe. El trabajo tuvo comoprincipales destinatarios a las escuelas secundarias dela región, y especialmente a las de la provincia de SantaFe. En este sentido, daremos cuenta del desarrollo dediferentes acciones implementadas durante los mesesde mayo a diciembre de 2018, que promovieron laarticulación entre la Educación Superior Universitariay las escuelas secundarias, con el objetivo de fomentary favorecer el ingreso a la universidad de los jóvenes.Asimismo, se buscó generar condiciones institucionalesy curriculares que posibiliten procesos genuinos deinclusión y permanencia en los estudios universitarios,así como también la continuidad de estudios superioresa través del trabajo articulado entre docentes y estudiantesde ambos niveles.

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Caiman latirostris is one of the two species of the order Crocodylia that inhabit Argentina and is considered a species of vital ecological and economic importance in the north-east of Argentina. In this region, pesticides are the most common contaminants in natural environments and wild caiman populations are subject to this contamination constantly. The aim of this study was to evaluate the effects the main pesticides used in the region: glyphosate (GLY), cypermethrin (CYP) and chlorpyrifos (CPF) -based formulations, as well as the mixture of them, on C. latirostris juveniles under semi-controlled condition of exposure ( ex-situ ) during 75 days. One hundred yearling caimans (10-month-old) were equally distributed into five experimental groups (20 animals per group): a negative control (NC -tap water), GLY 2% (Roundup® Full II formulation -RU), CYP 0.12% (Atanor® formulation), CPF 0.8% (Lorsban® formulation), and a mixture of the three pesticides (Mx3: GLY 2% + CYP 0.12% + CPF 0.8%). We applied early warning biomarkers to detect damage induced by these chemicals in peripheral blood: activity of the antioxidant enzymes catalase (CAT) and superoxide dismutase (SOD), analysis of lipid peroxidation (LPO) by the thiobarbituric acid reactive substances (TBARS), DNA damage and specific base oxidation through the standard and modified comet assay (CA), chromosome damage by micronucleus (MN) test and other nuclear abnormalities (NAs), hematological and growth parameters. Results showed a statistically significant increase in MN and NAs frequency, DNA damage, with an important contribution of base oxidation for all exposed groups compared to the NC. Total white blood cells count (TWBCC), and growth parameters showed effects mainly at the Mx3. The principal component analysis (PCA) demonstrated more sensitivity for biomarkers associated to genetic damage, including base oxidation to DNA than LPO, antioxidant enzyme modulation, immunotoxicity or growth parameters, to detect pesticides effects, applied under conditions similar to that found in natural environments.