Periodontitis is one of most common oral disease. Chronic periodontitis is characterised by gingival inflamation, periodontal pocket, lost of attachment, and alveolar bone loss. Smoking is a risk factor of periodontal disease that has direct effect to periodontal tissue. Smoking prevalence in Indonesia during 2013 was about 56,7% among men and about 1,9% among women. Smoking modifies the periodontal microbial challenge and host cytokine levels. Some studies showed that smoker has greater alveolar bone loss than non-smoker, and teeth that have the greatest alveolar bone loss are incisor and followed by molar. The aim of this study is to know the upper incisor and upper molar alveolar bone loss differences between smoker and non-smoker patient with chronic periodontitis. The study’s samples are 92 chronic periodontitis statuses and 200 periapical radiographs that selected by purposive sampling techinque. This study will measure the distance between cementoenamel junction to alveolar bone crest, cementoenamel junction to tooth apex, and alveolar bone loss percentage at upper incisor and upper molar. To compare the differences upper incisor and upper molar alveolar bone loss at patient with chronic periodontitis between smoker and non-smoker will be analyzed by independent t test and Mann-Whitney U test. The result showed that smoker has greater alveolar bone loss than non-smoker. There is no significant differences at upper incisor alveolar bone loss and there is significant differences at upper molar alveolar bone loss between smoker and non-smoker patient with chronic periodontitis.

Menopause describes the cessation of a woman’s menstrual period due to the ovaries’ shutdown of estrogen and progesterone production. Decreased levels of these hormones cause menopause symptoms and reduce the quality of life. Therefore, this study aims to determine how the quality of life of postmenopausal women and the practice of periodontics in Medan City are related to the condition of teeth. A descriptive method was used with a cross-sectional design to adapt the questionnaires. The number of samples was 60 people based on medical record data at the periodontics installation of the RSGM USU and dentists’ practice in Medan. Furthermore, a Likert scale was used to assess the quality of life of postmenopausal women with periodontitis. The results showed that the quality of life, which strongly influenced the teeth, was Stage IV Grade B. In terms of social relations, the most decisive influence on the condition of the teeth was appearance. The aspect of the physical ability which strongly influences the condition is chewing hard food. In conclusion, menopausal women with periodontitis influence their quality of life from aspects of physical ability, social relations, general health, and psychology. Key words: quality of life, menopausal women, periodontitis, dental conditions

Background: Andaliman (Zanthoxylum achantopodium DC) is an endemic plant that is found in the province of Sumatera Utara, Indonesia. It contains secondary metabolites, such as alkaloids, flavonoids, glycosides, saponins, tannins, and triterpenoids/steroids, which can potentially be used as a mouthwash. Streptococcus sanguinis and Staphylococcus aureus are the primary colonizing bacteria in plaque formation. Bacterial plaque is known to be the main cause of periodontal disease but can be controlled mechanically and chemically using mouthwash. Purpose: To determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of andaliman extract mouthwash (2%, 4%, 8%) against Streptococcus sanguinis ATCC®10556™ and Staphylococcus aureus ATCC® 25923™. Methods: This is a laboratory study with a post-test control-only design. The sample consists of andaliman extract mouthwash (2%, 4%, 8%), a positive control (chlorhexidine gluconate 0.2%), and a negative control (mouthwash formulation without andaliman extract) with three repetitions for each group. Data were analyzed with the one-way ANOVA test and post hoc LSD test. Results: The andaliman extract mouthwash with concentrations of 2%, 4%, and 8% significantly reduced the number of Streptococcus sanguinis and Staphylococcus aureus colonies (p<0.05), and there was a significant difference in the andaliman extract mouthwash with concentrations of 2%, 4%, and 8% compared to the negative control. Conclusion: Andaliman extract mouthwash with a concentration of 8% was more effective in inhibiting Streptococcus sanguinis growth than Staphylococcus aureus. The MIC values for both bacteria were 2%, but the study could not determine the MBC value.

Hyaluronic acid is known as hyaluronan or hyaluronate, which has the function of increasing the mediator of periodontal regeneration. Hyaluronate acid has many roles in the early stages of inflammation, such as providing a structural framework through the interaction of hyaluronate with fibrin clots that modulate host inflammation and infiltration of the extracellular matrix of cells at the wound site so that this material becomes a therapeutic material used in various fields, especially in the field of periodontics. All periodontal tissues have shown the presence of hyaluronate, which is specifically concentrated in non-mineral tissues such as gingiva and periodontal ligament, which affects the growth, development, and repair of tissues in periodontal disease. The role of hyaluronic acid in periodontal healing will be discussed in this article.

There are only few studies on the antibacterial activity of red fruit extract (Pandanus conoideus Lam) against oral pathogenic bacteria. Thus, this study aims to determine the effectiveness of red fruit extracts by looking at the Minimum inhibitory Concentrations (MIC) and Minimal Bactericidal Concentrations (MBC) against periodontal pathogenic bacteria. The subjects of this study were Streptococcus mutans (ATCC 25175), Fusobacterium nucleatum (ATCC 25586), and Porphyromonas gingivalis (ATCC 33277). The antibacterial effectiveness of red fruit extract was tested by the liquid dilution method (microdilution). The data were analyzed using the one-way ANOVA test followed by a double comparison test with the Post Hoc Least Significance Different (LSD) test method. The red fruit extract effectively inhibited and eliminated test bacteria (p <0.05). Our study showed that the red fruit extracts at a concentration of 20% could inhibit the growth of Streptococcus mutans and Porphyromonas gingivalis, which was determined as the MIC strength of 80% as MBC of both bacteria tested. Furthermore, red fruit extract at the concentration of 10% showed an inhibitory effect on the growth of Fusobacterium nucleatum, which was determined as MIC of Fusobacterium nucleatum and the strength of 40% as MBC of Fusobacterium nucleatum. The red fruit extracts were significantly effective against the growth of Streptococcus mutans, Fusobacterium nucleatum, and Porphyromonas gingivalis provide essential information for further in vivo clinical studies to determine the exact dosage and clinical effectiveness of periodontal disease.