Atopic diseases are multifactorial chronic disturbances which may evolve one into another and have overlapping pathogenetic mechanisms. Atopic dermatitis is in most cases the first step towards the development of the atopic march and represents a major socio-economic burden in the industrialized countries. The treatment of atopic diseases is often long-lasting and in some cases with lower effectiveness than expected.In order to prevent the development of the atopic march, the links between the atopic diseases have to be understood. The aim of this review is to present some major points outlining the link between atopic dermatitis and asthma, through a research in the medical literature from recent years.Stratifying patient populations according to the clinical phenotype of their disease and according to specific measurable values (biomarkers) can help to establish the main etiopathogenetic mechanisms of the disease in these populations. This will add predictive value for the evolution of the disease, and will allow the use and research of more targeted therapy in order to stop this evolution and comorbidities.
Background: This review aims to search the literature for possible cutaneous involvement in patients with COVID-19 infections. Such an analysis could provide dermatologists and other physicians with valuable information on the possible clinical manifestations of the disease as well as suggest a certain immunological pathway of the infectious process. Materials and Methods: A thorough search for the online literature available in scientific databases was conducted. Currently, data on cutaneous involvement is scarce, but, nonetheless, present. The papers found were divided into three categories-reported cases, exacerbations of preexisting skin diseases, and skin manifestations of preventive measures and treatment-and analyzed. Discussion: Dermatologists should take into consideration a COVID-19 infection in patients with diffuse exanthems, whether petechial, vesicular, urticaria-like, or otherwise. Specific patterns of lesions of the skin or of mucous membranes in COVID-19 infections have not yet been defined. Dermatologists should be expecting to deal with aggravated preexisting skin diseases, as well as deal with and minimize skin problems caused by the use of personal protective equipment (PPE).
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