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The epidermal nevus syndrome is a disease complex consisting of the association of an epidermal nevus with various developmental abnormalities of the skin, eyes, nervous, skeletal, cardiovascular, and urogenital systems. The epidermal nevi are classified according to their predominant component; nevus sebaceus (sebaceous glands), nevus comedonicus (hair follicles), and nevus verrucosus (keratinocytes). We report a neonate who presented with a nevus sebaceus on the scalp and face as well as a coloboma and dermoid on his left eye. Within the sebaceous nevus on the scalp, circumscribed lesions of aplasia cutis congenita were detected, which is consistent with the recently proposed term in the literature didymosis aplasticosebacea.

Background: This review aims to search the literature for possible cutaneous involvement in patients with COVID-19 infections. Such an analysis could provide dermatologists and other physicians with valuable information on the possible clinical manifestations of the disease as well as suggest a certain immunological pathway of the infectious process. Materials and Methods: A thorough search for the online literature available in scientific databases was conducted. Currently, data on cutaneous involvement is scarce, but, nonetheless, present. The papers found were divided into three categories-reported cases, exacerbations of preexisting skin diseases, and skin manifestations of preventive measures and treatment-and analyzed. Discussion: Dermatologists should take into consideration a COVID-19 infection in patients with diffuse exanthems, whether petechial, vesicular, urticaria-like, or otherwise. Specific patterns of lesions of the skin or of mucous membranes in COVID-19 infections have not yet been defined. Dermatologists should be expecting to deal with aggravated preexisting skin diseases, as well as deal with and minimize skin problems caused by the use of personal protective equipment (PPE).

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