An efficient synthesis of alkyl 7-hydroxy-1-oxo-1,2,3,4tetrahydropyrrolo[1,2-a]pyrazine-8-carboxylate derivatives by reaction between diamines, dialkyl acetylenedicarboxylates, and alkyl or aryl glyoxales is reported. Ease of handling, easy purification, and good yields are the main advantages of the presented method.
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