Among the late effects of poliomyelitis is the Post-Polio Syndrome (PPS), characterized by increased muscle strength loss, abnormal fatigue and pain after a period of stability of at least 15 years. The incidence and prevalence of PPS are unknown in the world and in Brazil, depending on the diagnostic criteria. The diagnosis of PPS is made by exclusion and there is no specific laboratory test, these only help to rule out other diseases. There is no curative treatment for PPS. Its etiology remains unknown. Strategies for their clinical management aim reducing muscle overusing and a balance active lifestyle is recommended to minimize the symptoms.
Introdução. A Usabilidade se define como a facilidade do usuário em aplicar uma tecnologia a fim de realizar uma tarefa específica com eficácia, eficiência e satisfação. No desenvolvimento de Tecnologias Assistivas, é importante a inclusão do usuário, bem como a utilização de testes antes, durante a após a confecção destas visando obter altos padrões de usabilidade, evitando desgaste mental e psicológico e abandono de tecnologia. O objetivo foi avaliar a Usabilidade da Tecnologia Assistiva de Comunicação Aumentativa Eye Tracking. Método. Cinco profissionais da área da informática de ambos os sexos, com média de 5,7 anos de formação em: ciência da computação e análise e desenvolvimento de sistemas. Estes responderam um questionário para avaliação da Usabilidade após realizarem um teste com a tecnologia. Os testes foram divididos em etapas, com tempos determinados, abrangendo o recebimento, conexão dos itens, instalação, configuração dos softwares e realização de uma tarefa. Resultados. A maioria dos profissionais encontrou dificuldades no posicionamento e calibração do software e no idioma. Houve desistência de 20%. Conclusão. Foi possível avaliar a usabilidade da tecnologia indicando caminhos para o aperfeiçoamento de um manejo mais eficaz, eficiente e satisfatório para o usuário.
Verify if L-carnitine associated with Piracetam in fixed dose combination can improve fatigue and MS in patients with Post-Poliomyelitis Syndrome (PPS) and verify the tolerability and safety of the combination.
Materials and methods
Design and sample sizeThis was a double-blind randomised controlled clinical trial with 2:1 factorial design for the experimental group. The study was performed at the PPS outpatient clinic of the Department of Neuromuscular Diseases, Federal University of São Paulo (UNIFESP) in the years of 2017 and 2018.
Post-Polio Syndrome (PPS) is characterized by the appearance of new muscular symptoms or worsening of previous residual symptoms, several years after the acute polio. The most common symptoms include a trial of fatigue, deterioration in muscle strength and pain. Fatigue is one of the most frequent complaints of PPS and the majority of patients identify fatigue as their most troubling symptom. The aetiology of the symptom arouses great interest, mainly due to its multifactorial character, and can be divided into two components: peripheral (muscular) fatigue and central (general) or simultaneously-occurring fatigue. Considering the importance of the symptom and the limitations that can cause in PPS patients, it is important to consider a series of variables, so that it can be better understood, thus providing a more effective and specific treatment.
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