'See and treat' protocol is a well-accepted, feasible and useful option for management of high-grade CIN in Bangladesh. It reduces the number of visits to the clinic and failure to receive treatment.
The purpose of this study was to detect elevated uric acid level in maternal blood, presumably due to decrease renal urate excretion, for early detection of hypertensive disorder in pregnancy. This study showed that serum uric acid was significantly elevated in all cases of preeclampsia. The present study showed that serum uric acid levels were significantly elevated in eclampsia as compared with the levels in pregnancies complicated by hypertension (p<0.05). The level of uric acid above 4.5 mg/dl is indicative of preeclamptic process and in such cases; the subjects deserve careful and close clinical follow up. Increasing higher concentration of uric acid i.e. 5.7 mg/dl, 6.3mg/dl, and 6.72mg/dl was observed in pregnancy with chronic hypertension, preeclampsia and eclampsia respectively. These results showed that serum uric acid could be used as a sensitive indicator of severity of preeclampsia. Out of 100 cases, there were 20 preterm baby and others such as stillbirth and IUD. So, these entire abnormal fetal outcomes were in the hyperuricaemic group and 5.37 times higher as compared to low serum uric acid group. Mean birth weight of preeclampsia and eclampsia were 2.31kg and 2.30kg respectively compared with 2.5kg in chronic hypertension group.
It is a case control study which was design to know the association of serum Lipoprotein (a) level in preeclamptic (PE) in women. This study was carried out in department of Obstetrics and Gynecology, Sir Salimullah Medical College Hospital, Mitford, Dhaka. Total number of subjects was 100. Out of which 50 were cases and 50 were controls. Cases were physically and clinically proved PE patients. Controls were age, parity and gestational age matched. Three ml of blood were collected from each subjects, serum fasting LP(a) level were measured The mean age of study group was 24.49 ± 6.48 years. Serum Lipoprotein(a) level was 51.51 ± 29.38mg/dl Vs 17.40 ± 7.89 mg/dl in cases and controls respectively. This difference was statistically significant (p<0.001). Mean serum Lipoprotein(a) level was found to be raised in severe preeclampsia (74.87mg/dl) and lowest in control subject Severe preeclampsia was found to be associated with higher level of lipoprotein (a) than both control (p<0.01) and mild preeclamptic (p<0.01) subjects. Mild preeclampsia was also found to have higher average serum Lipoprotein (a) than the normal (P<0.01) subjects.
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