Penelitian ini bertujuan untuk mengkaji aktivitas antibakteri infusa daun lidah buaya (Aloe barbadensis Miller) pada bakteri Pseudomonas aeroginosa, Salmonella typhi, Staphylococcus aureus, dan Streptococcus pneumonia. Penelitian ini dilakukan dengan metode difusi sumuran untuk menguji aktivitas antibakteri infusa daun lidah buaya pada konsentrasi 20, 40, dan 60% sebagai antibakteri terhadap bakteri Pseudomonas aeroginosa, Salmonella typhi, Staphylococcus aureus, dan Streptococcus pneumonia. Aktivitas antibakteri ditunjukkan dengan terbentuknya zona bening di sekitar sumuran. Infusa daun lidah buaya pada konsentrasi 60% dapat menghambat pertumbuhan bakteri Pseudomonas aeroginosa yang ditunjukkan dengan terbentuknya zona bening sebesar 16,5 mm, bakteri Salmonella typhi sebesar 34 mm, dan Staphylococcus aureus sebesar 15 mm. Infusa daun lidah buaya pada konsentrasi 60% tidak dapat menghambat pertumbuhan bakteri Streptococcus pneumonia yang ditunjukkan dengan tidak terbentuknya zona bening di sekitar sumuran. Oleh karena itu, infusa daun lidah buaya dapat digunakan sebagai agen antibakteri bakteri patogen Pseudomonas aeroginosa, Salmonella typhi, dan Staphylococcus aureus
Cancer is the second cause of death in the world after heart disease. Cancer therapy using natural product was considered has no side effect. Secondary metabolites from ketapang (Terminalia cattapa L) leaves has a prospect for cancer therapy. The objective of this research was to determine the cytotoxical effect of ketapang leaves on T47D breast cancer cells. Ketapang leaves were macerated using chloroform, ethyl acetate and methanol. Cytotoxicity effect were determined using MTT Cell Viability Assay. The result showed that chloroform, ethyl acetate and methanol extract were not able to reduce cell viability of T47D cells. Key words: cancer, ketapang, T. cattapa, cytotoxic, T47D cells.
This study aims to examine the potential of jamu inggu as an alternative antibacterial herb that can be used against Staphylococcus aureus, Streptococcus pnuemoniae, S. Pyogenes, and Pseudomonas aeruginosa that is causing Upper Respiratory Infections (URI). Antibacteria activity test of jamu inggu was using the Agar diffusion method by Kirby-Bauer. To test jamu inggu antibacterial activity against Staphylococcus aureus,Streptococcus pnuemoniae, S. Pyogenes, and Pseudomonas aeruginosa, the diameter of the test bacteria growth inhibition zone was measured. The formation of a clear zone around the disc indicates that jamu inggu has chemical compounds that are antibacterial against Staphylococcus aureus,while the Pseudomonas aerugenosa, Streptococcus pyogenes, and S. pneumoniae bacteria cannot be inhibited by jamu inggu. It was indicated by no formation of a clear zone around the disc. Result shows that jamu inggu can be used as an alternativesource of antibiotics against the Staphylococcus aureus
This study was aimed at determining the relationship between the Pediculus humanus capitis infestation condition, anemia status and learning achievement in primary school-age children. This study was conducted at SD Bangunharjo Sewon Bantul, Yogyakarta. This study is an observational analytic study with cross sectional design in which the variables are measured in one measurement without intervening. The data obtained through pediculosis examination, Hb examination, and measurement of learning outcomes. The data then were analyzed descriptively presented in tabular form, then performed statistical analysis using the chi-square test. The results show that the students suffering from pediculosis, 57.9% also suffering from anemia and 51.0% having poor category achievement. In line with other researchers, one of the factors that influence one’s learning achievement is the memory factor. Someone’s anemia status can affect one’s memory. The prevalence of Pediculus humanus capitis infestation is 38.3%. Chi-square test showed a significant relationship between Pediculus humanus capitis infestation condition, anemia status, and learning achievement.HUBUNGAN PEDIKULOSIS KAPITIS, STATUS ANEMIA DAN PRESTASI BELAJAR PADA SISWA SEKOLAH DASAR Penelitian ini bertujuan untuk mengetahui hubungan kejadian infestasi Pediculus humanus capitis (kutu kepala) dengan status anemia dan prestasi belajar pada anak usia sekolah dasar. Penelitian ini dilakukan di SD wilayah Bangunharjo Sewon Bantul Yogyakarta. Penelitian ini merupakan penelitian analitik observasional dengan desain cross sectional. Variabel diukur dalam satu kali pengukuran dengan tidak melakukan intervensi. Data penelitian diperoleh melalui pemeriksaan pedikulosis, pemeriksaan Hb, dan pengukuran hasil belajar. Data dianalisa secara deskriptif yang disajikan dalam bentuk tabel, kemudian dilakukan analisis statistik menggunakan Uji chi-square. Hasil penelitian ini menunjukan bahwa menderita pedikulosis sebesar 57,9% menderita anemia dan sebesar 51,0% dengan prestasi belajar kategori kurang baik. Salah satu faktor yang mempengaruhi prestasi belajar seseorang yaitu faktor daya ingat. Status anemia seseorang dapat mempengaruhi daya ingat seseorang. Prevalensi infestasi Pediculus humanus capitis sebesar 38,3%. Uji chi-square menunjukkan adanya hubungan yang signifikan antara kejadian infestasi Pediculus humanus capitis dengan status anemia dan prestasi belajar.
Diabetes mellitus is a metabolic disorder with hyperglycemia. The amount of diabetic patients in Indonesia will increase rapidly without suitable treatment. High level of blood glucose will trigger oxidative stress. The objective of this research wa to investigate the effect of lemongrass on oxidative stress response that was indicated by serum and hepatic Total antioxidant capacity and Malondialdehyde level. Thirty male wistar rat were divided into five groups. K1 was a normal group, K2 was a normal group with lemongrass treatment, K3 was a diabetic group induced by a single dose of Streptozotocin at a concentration of 60 mg/kg body weight, K4 was a diabetic group that was treated with glibenclamid at a concentration of 0.09 mg/200 gr body weight, while K5 was a diabetic group treated with lemongrass at a concentration of 3.6 ml/200 gr body weight. The result showed that lemongrass was able to reduce blood glucose levels, serum MDA and hepatic MDA levels and increased the level of total antioxidant status Diabetes adlah kelainan metabolisme yang ditandai dengan hiperglikemia. Jumlah penderita diabetes mellitus di Indonesia akan mengalami peningkatan jika tidak ada penanganan yang sesuai. Tinggi kadar glukosa darah dapat memicu terjadinya stress oksidatif. Tujuan penelitian ini adalah untuk mengetahui pengaruh pemberian sereh terhadap respon stress oksidatif yang ditunjukan dengan kapasitas antioksidan total dan kadar malondialdehid. Tigapuluh ekor tikus wistar jantan dibagi menjadi lima kelompok. K1 adalah kelompok normal, K2 adalah kelompok normal dengan perlakuan sereh, K3 adalah kelompok diabetes yang diinduksi dengan streptozotocin 60 mg/kg berat badan single dose, K4 adalah kelompok diabetes yang diberi perlakuan dengan glibenklamid dengan dosis 0.09 mg/200 gr berat badan. Sedangkan K5 adalah kelompok diabetes yang dieri perlakuan dengan rebusan sereh dengan dosis 3.6 ml/200 gr berat badan. Hasil penelitian menunjukan bahwa rebusan sereh mampu menurunkan kadar glukosa darah, konsetrasi malondialdehid serum dan hepar, serta meningkatkan total antioksidan status pada serum dan hepar.
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