Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a disease characterised by infiltration of the myocardium by adipose and fibrous tissue. The disease is an important cause of sudden death in humans, but has rarely been described in animals. This report describes ARVC in two cats with right-sided congestive heart failure. One cat had also experienced previous episodes of syncope. Standard six-lead and 24-hour (Holter) electrocardiogram recording revealed complete atrioventricular block and multiform ventricular ectopics in both cats, with the addition of ventricular tachycardia, ventricular bigeminy and R-on-T phenomenon in one of them. On echocardiography, the right ventricle and atrium were massively dilated and hypokinetic. The survival times of the cats were three days and 16 days following diagnosis. Histopathology in one case revealed fibro-fatty infiltration of the myocardium, predominantly affecting the right ventricular free wall.
Summary Following the derivation of resultant cardiac dipole moments from the integration of body surface potentials throughout the cardiac cycle in three horses previously reported, this paper describes observations on the same animals to determine the siting of bipolar leads in the three body axes to produce vectorcardiograms similar to those from the dipole moment studies. The results were compared with those using Einthoven's system. The experimental leads gave more accurate portrayal of the cardiac electric field than the conventional Einthoven's triangle which particularly in the horizontal plane was not representative of the cardiac electric forces. Résumé Cet article décrit l'emplacement des dérivations bipolaires suivant trois axes qui permettent d'obtenir des vectocardiogrammes comparables à ceux obtenus précédemment (étude de la résultante des moments du dipole cardiaque lors de la révolution cardiaque à partir du champ électrique superficiel). Les résultats sont comparés à ceux obtenus par la méthode d'Einthoven. Les dérivations expérimentales donnent une image plus précise du champ électrique du coeur que ne le font celles dessinant le triangle d'Einthoven. Ce dernier, notamment dans le plan horizontal, n'est point chez le Cheval représentatif des forces électriques du coeur. Zusammenfassung In einem früheren Bericht wurde die Bestimmung kardialer Dipolmomente beschrieben, die auf Grund der Integration von Körperoberflächen‐Potentialen während des ganzen kardialen Zyklus bei 3 Pferden gewonnen werden konnten; der vorliegende Artikel beschreibt nun die Beobachtungen an den gleichen Pferden, die gemacht worden sind, um die Placierung bipolarer Ableitungen in den 3 Körperachsen zu bestimmen. Mit ihrer Hilfe können Vektorkardiogramme gewonnen werden, die mit denjenigen der Dipolmoment‐Untersuchungen vergleichbar sind. Die Resultate werden mit Befunden verglichen, die mit Einthoven's Ableitungen erhalten wurden. Die experimentellen Ableitungen haben eine genauere Analyse des kardialen elektrischen Feldes erlaubt als das konventionelle Einthoven'sche Dreieck, das besonders in der horizontalen Ebene nicht repräsentativ ist für die elektrischen, kardialen Kräfte.
Aujeszky's disease occurred in a pack of harrier hounds in the south west of England and caused the death of 11 of a pack of 51 animals. The onset appeared to have followed the feeding of pig carcase material from a very large fattening unit. No evidence of clinical disease was seen in pigs in this unit, but serological evidence of earlier infection was obtained. Interesting lesions in the intestinal wall of the hounds are described.
The clinico‐pathological findings are described in thirteen young dogs with advanced renal disease. All but three dogs were less than 2 years old. Some had signs of renal dysfunction since birth. Presenting signs were variable but anorexia, lethargy and weight loss were most frequent. All dogs had raised blood urea levels and most passed dilute urine; proteinuria and anaemia were variable findings. At necropsy all dogs had extra‐renal lesions of renal failure and finely granular or lobulated, shrunken kidneys. The microscopical appearances of the kidneys were not those of amyloidosis, inflammatory or glomerular disease but were considered likely to be of developmental origin. The renal lesions were divided into three histologically distinct groups. Predominantly cystic and connective tissue changes, characterized by striking dilatation of glomerular capsular spaces and cortical tubules. Atypical connective tissue changes in which there were segmental bands of fibrous tissue containing primitive glomerular and tubular structures. Predominantly glomerular and connective tissue changes, characterized by varying degrees of glomerulosclerosis and widespread calcification of glomeruli, tubules and blood vessels. All groups had cortical and medullary interstitial fibrosis but minimal inflammatory cell infiltrates.
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