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The objective of this study is to develop an ensemble classifier with Merit Merge feature selection that will enhance efficiency of classification in a multivariate multiclass medical data for effective disease diagnostics. The large volumes of features extracted from brain Magnetic Resonance Images and neuropsychological tests for diagnosis lead to more complexity in classification procedures. A higher level of objectivity than what readers have is needed to produce reliable dementia diagnostic techniques. Ensemble approach which is trained with features selected from multiple biomarkers facilitated accurate classification when compared with conventional classification techniques. Ensemble approach for feature selection is experimented with classifiers like Naïve Bayes, Random forest, Support Vector Machine, and C4.5. Feature search is done with Particle Swarm Optimisation to retrieve the subset of features for further selection with the ensemble classifier. Features selected by the proposed C4.5 ensemble classifier with Particle Swarm Optimisation search, coupled with Merit Merge technique (CPEMM), outperformed bagging feature selection of SVM, NB, and Random forest classifiers. The proposed CPEMM feature selection found the best subset of features that efficiently discriminated normal individuals and patients affected with Mild Cognitive Impairment and Alzheimer's Dementia with 98.7% accuracy.

<span>Variable Selection is the most essential function in predictive analytics, that reduces the dimensionality, without losing an appropriate information by selecting a few significant features of machine learning problems. The major techniques involved in this process are filter and wrapper methodologies. While filters measure the weight of features based on the attribute weighting criterion, the wrapper approach computes the competence of the variable selection algorithms. The wrapper approach is achieved by the selection of feature subgroups by pruning the feature space in its search space. The objective of this paper is to choose the most favourable attribute subset from the novel set of features, by using the combination method that unites the merits of filters and wrappers. To achieve this objective, an Improved Hybrid Feature Selection(IMFS) method is performed to create well-organized learners. The results of this study shows that the IMFS algorithm can build competent business applications, which have got a better precision than that of the constructed which is stated by the previous hybrid variable selection algorithms. Experimentation with UCI (University of California, Irvine) repository datasets affirms that this method have got better prediction performance, more robust to input noise and outliers, balances well with the available features, when performed comparison with the present algorithms in the literature review.</span>

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