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Introduction: Fixed orthodontic appliances with its various components cause inaccessible areas for plaque and make tooth cleaning difficult. Several chemical formulations have been used for mechanical cleaning, but due to their unpleasant side-effects researchers now concentrate on herbal drugs. Aim: To determine the antibacterial effect of carrot extract on Lactobacillus, Aggregatibacter actinomycetemcomitans and Streptococcus mutans. Materials and Methods: This was an in-vitro study conducted to determine the antibacterial activity of Daucus carota subsp. sativus (carrot) extract against Lactobacillus, Aggregatibacter actinomycetemcomitans and Streptococcus mutans. A 500 grams of healthy and mature carrots were cleaned, washed and peeled then dried in a hot air oven at 40°C for 5 days and then ground. Ground powder was mixed with distilled water and ethanol to obtain the aqueous and ethanolic extract respectively. The antimicrobial activity of these extracts was studied using well diffusion methods in culture plates under three different concentrations. Antimicrobial activity was studied by measuring the area of inhibition. Cytotoxic activity of the samples was also assessed. Kruskal-Wallis test was performed to compare antimicrobial activity of aqueous and ethanolic extract mouthwash. Results: Aqueous mouthwash showed moderate antimicrobial activity without statistically significant difference against S.mutans (p-value=0.06), Lactobacillus sp. (p-value=0.7), or A. Actinomycetemcomitans (p-value=0.16) microbes, at three different concentrations. Ethanolic extract had moderate antimicrobial activity against all the three microorganisms, but more significant at 100 microlitre concentrations with a p-value of 0.03 against S. mutans. The cytotoxic effects of the ethanolic and aqueous mouthwashes were less cytotoxic at minimal concentrations. Conclusion: Extract derived from Daucus carota was proven to possess antimicrobial activity against S.mutans, A.actinomycetemcomitans and Lactobacillus. Further research is required to advocate its efficacy at lower concentrations.

Orthodontic treatment often faces challenges in achieving proper anchorage. While orthodontic mini-implants have gained popularity, no universally accepted design and insertion protocol exists for these implants. However, their relatively modest failure rate indicates their clinical reliability. To address complex geometries in the maxilla and mandible, patient-specific implants (PSIs) have emerged as a solution. PSI is currently employed in various domains of oral and maxillofacial surgery like temporomandibular joint (TMJ), total joint replacement, reconstruction of the facial skeleton, and orthognathic surgery. PSI allows for the creation of customized implant fits, leading to shorter rehabilitation times. This case report presents a multidisciplinary approach involving oral surgery and orthodontics, specifically focusing on the design of PSI, surgical placement of PSI, and use of PSI in maxillary protraction in orthodontics. The report highlights the design process of designing PSI and emphasizes its role in orthodontic treatment. By incorporating PSI as a temporary anchorage device (TAD), enhanced stability, precise control over tooth movement, and accurate repositioning of jaws can be achieved. The collaborative effort between orthodontists and oral surgeons is crucial in integrating PSI into the overall treatment plan. Despite the higher costs associated with PSI, their numerous advantages outweigh these drawbacks. PSI plays a vital role in providing enhanced stability, appropriate treatment plan, and achieving desired treatment in orthodontic and oral surgery procedures.