No abstract

To find out the association of serum homocysteine levels and serum vitamin B-12 levels in patients with retinal vein occlusion.Patients of all age group and any sex who are coming in vitreoretinal OPD of department of ophthalmology at a tertiary care hospital of Western Maharashtra were studied. 50 cases of RVO and same number of age and sex matched controls were taken into consideration. All patients were underwent for assay of serum homocysteine by ECLIA method and serum Vitamin B12 by CMIA method.The highest number of cases were of BRVO (60%) followed by CRVO (30%) and only one case of TVO (2%) was noted. The average level of homocysteine in RVO and control group is found to be 23.80 and 12.43 whereas the standard deviation of homocysteine level in RVO group is 13.28 and control group is 10.58. Therefore levels of homocysteine are significantly higher in RVO group in comparison with control group. Vitamin B-12 level was 455.86 in control group and 325.8 in RVO group. The P value suggests that, Vitamin B12 was significantly lower in case group compared to controls. Vitamin B-12 levels were significantly lower in cases with a higher Homocysteine level. Hype-rhomocysteinemia and hypovitaminosis B12 is significantly present in cases of retinal vein occlusion irrespective of types and underlying systemic diseases.

No abstract

Background: Aphakia is the most dreaded and inadvertent complication of cataract surgery. Visual rehabilitation with wide variety of surgical options is a challenge for the ophthalmologist. Our study evaluates the safety and efficacy of the retropupillary implantation of the iris-fixated intraocular lens (IOL) in a 2-month follow-up period. Aims: This study aims to assess the visual outcome, identify complications, and assess the long-term stability of eyes undergoing retropupillary iris-claw lens implantation for aphakia. Settings and Design: This was a prospective interventional study (single-group, before–after study). Materials and Methods: Sixty eyes with surgical aphakia fulfilling the inclusion criteria were considered. Preoperatively, evaluation of visual acuity, slit-lamp examination, fundus examination, intraocular pressure, corneal endothelial cell count, macular thickness, and edema was done. Anterior vitrectomy was done, and retropupillary iris-claw lens was implanted. Postoperative best-corrected visual acuity (BCVA), IOP, corneal endothelial cell density, macular edema, and IOL stability were evaluated. Statistical Analysis: The computer software statistical package for the social sciences, version 20.0 (SPSS) was used, and a 0.05 level of significance was considered. Results: The major cause of aphakia was posterior capsular rupture (55%). Postoperative BCVA on day 60 was 6/6–6/18 in 83.33% of cases. Three patients had disenclavation of the haptic which required retucking of IOL. No patient had corneal decompensation, cystoid macular edema, or IOP rise. Conclusion: Our results demonstrate that retropupillary technique of iris-claw implantation is a safe and effective method for visual rehabilitation in aphakic patients. This surgical procedure has an advantage of posterior chamber implantation with a low intraoperative and postoperative complication profile.

No abstract