Imaging plays a vital role in the evaluation of adrenal pathology. The most widely used modalities are computed tomography and magnetic resonance imaging. Alone or in conjunction with appropriate clinical and biochemical data, imaging can provide specific diagnoses that preclude the need for tissue sampling. This article reviews imaging features of normal and diseased adrenals, from both benign and malignant causes.
O hamartoma fibrolipomatoso neural e a macrodistrofia lipomatosa são doenças raras, com achados de imagem característicos. Radiografias simples, estudos de ressonância magnética e prontuários médicos de quatro pacientes foram revisados. Em um paciente, foi realizada cirurgia com confirmação histopatológica. Em três pacientes, os achados clínicos e de imagem foram considerados suficientes para o diagnóstico. Descrevemos dois casos de macrodistrofia lipomatosa isolada, um caso de hamartoma fibrolipomatoso do nervo mediano e um caso de coexistência das duas condições. As radiografias simples, nos casos de macrodistrofia lipomatosa, mostraram aumento difuso de partes moles e estruturas ósseas, com estrias radiotransparentes entremeadas às fibras musculares. Os dois casos de hamartoma fibrolipomatoso ocorreram no nervo mediano, com achados, à ressonância magnética, de fascículos nervosos espessados com baixo sinal nas imagens ponderadas em T1 e T2, com infiltração homogênea de gordura entre estes, aparecendo com alto sinal em T1 e baixo sinal em T2 com saturação de gordura. O aspecto do nervo aos cortes axiais é de "cabo coaxial". Nota-se extensão para a ramificação dos nervos, aspecto típico desta lesão. As características de imagem da macrodistrofia lipomatosa e do hamartoma fibrolipomatoso neural, principalmente pela ressonância magnética, permitiram o diagnóstico preciso destas condições freqüentemente coexistentes.
Coelho et al.: Energy budget in juvenile whiteleg shrimp 1 Energy budgets for juvenile Pacific whiteleg shrimp Litopenaeus vannamei fed different diets Energy budgets for juvenile Pacific whiteleg shrimp, Litopenaeus vannamei (1.7-4.0 g) fed with different diets were assessed. The energy partitioning between growth, respiration, ammonia excretion, feces and exuvia was calculated to estimate for total food energy intake. Shrimp oxygen consumption and ammonia excretion were quantified in sealed chambers (25°C, 34 ppt). Energy allocated for growth and feces were obtained from the wet combustion of whole body and feces samples, exuvia was estimated as 10% growth energy. Three diets were tested: 100% chopped fish (Fish), 100% commercial feed (Feed), and 50-50% chopped fish and commercial feed (Mix). Most of the energy from the diets was channeled into respiration (49.7-70.5%). Shrimp fed the Feed diet used more energy in growth (24.4%) than those fed Mix (13.4%) or Fish diets (13.2%), either in absolute (joule) or relative (% of ingested energy) terms. Conversely, energy loss as ammonia excretion was lower in shrimp fed Feed (1.0%) compared to shrimp fed Mix (4.2%) or Fish diets (7.8%). Less energy was lost in feces by shrimp fed Fish diet (7.3%) compared to Mix (20.2%) and Feed diets (22.2%). The calculated energy intake by shrimp fed Fish, Mix and Feed were 0.995, 1.100, and 1.255 kJ ind-1 day-1 , respectively. According to the O:N atomic ratios (oxygen consumed to nitrogen excreted), protein tented to be the predominant substrate catabolized by shrimp fed Fish (O:N=16±5.2), and Mix (O:N=25±11.6), with increasing use of carbohydrates and/or lipids in the Feed (O:N=74±37.3). Results suggest diet composition may affect energy budget and partitioning differently between metabolism and growth either in absolute or relative terms, as shrimp fed Fish and Mix diets used protein as main substrate for metabolism, whereas shrimp fed Feed diet channeled protein for growth, and lipids and carbohydrates for other metabolic functions.
Prostate cancer plays an important role in widely understood aspects of men's health, and is becoming a growing problem in terms of public life. Prostate cancer is one of the most common neoplasms among men. Male patients can live with prostate cancer for a long time so it is important to offer appropriate males adequate diagnostic tools and treatments. Prostate cancer and PSA potentially represent a “pair” of a disease and an appropriate indicator to be used in mass screening, but regardless of that there is still active debate about it. Extensive use of PSA screening has modified epidemiology of the diseases. Randomized controlled studies provided sufficient results regarding a reduction in mortality through PSA mass screening, while all agreed on risks of overdiagnosis and overtreatment. New and accurate screening tools are necessary, along with adequate counseling and risk stratification.
OBJETIVO: Avaliar a frequência de hipervascularização pela visualização de vasos no interior ou ao redor de metástases ósseas de carcinoma de células renais. MATERIAIS E MÉTODOS: Foram avaliados, retrospectivamente, exames de ressonância magnética de 13 pacientes com diagnóstico de carcinoma de células renais, com 15 lesões ósseas metastáticas, que não haviam sido submetidos a nenhum tratamento. RESULTADOS: Foram encontrados sinais de hipervascularização em 12 das 15 lesões (80%), sendo 6 na coluna lombar, 3 na bacia, 1 na coluna torácica, 1 na ulna e 1 na tíbia. CONCLUSÃO: A alta frequência de hipervascularização em metástases ósseas de carcinoma de células renais encontrada neste trabalho pode sugerir a etiologia renal, tornando-se muito útil na apresentação clínica usual de lesão óssea única com neoplasia primária desconhecida.
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