Traditional asymmetric supercapacitors are severely restricted due to the low specific capacitance of carbon negative materials. The rational design of positive and negative electrodes that afford the asymmetric device with high performances is particularly important. In this paper, we fabricate a novel cost-effective and environmental-friendly aqueous asymmetric supercapacitor by using CuCo 2 O 4 /CuO nanowire arrays as positive electrode and RGO/Fe 2 O 3 composites as negative electrode. The assembled device exhibits a high energy density of 33.0 Wh kg -1 at a power density of 200 W kg -1 , and can still operate at a high power density of 8.0 KW kg -1 with an energy density of 9.1 Wh kg -1 . The current strategy will provide a fresh route for design and fabricate of novel asymmetric supercapacitors with both high energy density and high power density.

Background: Osteosarcoma, a primary malignant bone tumor derived from mesenchymal tissue, is the most common type of pleomorphic tumor that occurs in children and adolescents. The aim of this study was to compare the efficacy and safety of high-dose methotrexate (M), doxorubicin (D), cisplatin (C), and ifosfamide (I) in the management of osteosarcoma. Methods: Electronic databases including PubMed, Cochrane Library, and Embase database were searched for studies published from when the databases were established to July 13, 2019. The network meta-analysis was performed using software R 3.3.2 and STATA version 41.0 after demographic and outcome data extraction. The ranks based on probabilities of interventions for each outcome were performed. In addition, the consistency of direct and indirect evidence was assessed by node splitting. Results: The network meta-analysis results revealed that MDCI had a significant lower hazard risk of overall survival [MDCI vs MDC: HR = 0.74, 95% CrI (0.23, 0.87); MDCI vs DC: HR = 0.60, 95% CrI (0.16, 0.92)]. In addition, MDCI had a clearly longer progression-free survival time than that of DC [MDCI: HR = 0.88, 95% CrI (0.46, 0.98)]. No significant difference was detected in MDC and DC in OS, PFS, and AEs. The probabilities of rank plot showed that MDCI ranked first in OS (73.12%) and PFS (52.43%). DC was the best treatment in safety, ranked first (75.43%). Conclusions: MDCI showed its superiority among all chemotherapeutic agents in relation to efficacy and safety, followed by MDC. In addition, MDCI was associated with an increased risk of AEs. According to our analysis, DC was less effective but safer for MDC and MDCI.

Centimeter-sized CsPbBr3−3nX3n single crystals were grown using the modified Bridgman method. Eight filter-free narrowband photodetectors were fabricated based on the CsPbBr3−3nX3n crystals utilizing the concept of charge collection narrowing. A filter-free color image sensor was constructed using these eight CsPbBr3−3nX3n narrowband photodetectors.

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An ultra-thin, planar, broadband metalens composed of L-shaped gap antennas on a thin gold film has been designed, which is suitable for both circular and X/Y linear polarizations focusing simultaneously. The phase discontinuity of the cross-polarized transmisson light can be manipulated by the length and width of the L-shaped gap antenna accurately. The designed planar metalens posses a strong focusing ability over a large wavelength range, and the size of the focus spot is in sub-wavelength scale. The focal lengths change from 13 to 7 um with incident wavelength from 750 to 1300 nm, and the cause of dispersion is explained and analyzed in detail. The designed metalens can work very well at a wide incident angles of 0~45°. Most importantly, its unique focusing ability that is independent of the incident polarizations will greatly promotes the practical applications and developments of the metasurfaces.