The article presents data on the effect of soil mixtures on tomato seedlings of two varieties: «Novichok» and «Velmozha», since the right choice of components in the composition of soil mixtures will depend on obtaining healthy, properly formed tomato seedlings. Field soil with addition of peat, biohumus and horse mulch in different ratios was used as the main component in all the variants. According to the data obtained, the greatest biometric indicators tomato seedlings of the two varieties form in the variants with field soil and biohumus (1:1), field soil and horse mulch (2:1). These soils contribute to better growth and development of seedlings, the formation of its more ramified powerful root system, which provides the most favorable conditions for nutrient, water and air conditions, the photosynthetic activity of plants when transplanted into the open field, leading to an increase in productivity by 1,3–2,2 times, depending on the variety. In the variant with peat the tomato seedlings were stunted (4,6–4,9 cm) with a weak root system (1,6–2,2 cm); they were not transplanted to the open ground.

This article describes the concept, specifics, benefits of collaborative learning technology, the technological process of group work and pupils’ thinking. The purpose of the article is to study the use of collaborative learning technology for the development of pupils' creativity in biology lessons. The main methods of the study are the analysis of the works of domestic and foreign scientists, scientific literature for group work aimed at developing the creative abilities of pupils. In the course of writing the article are studied and explained the processes of collaborative learning technology, the specifics of the organization of group work, the basic ideas of joint training, the thinking abilities of people, the process of creative thinking, the types of group work used in biology classes.In addition to solving cognitive and creative goals, collaborative learning provides for solving psychological and social problems, a culture of communication is formed during the task. The main idea of collaborative learning technology is to create conditions for active learning activities of pupils in different learning situations.

Environmental pollution against the background of harsh climatic conditions greatly aggravates the situation, creates more difficult conditions for the organism to adapt to environmental factors, while reducing the reserve capacity of the organism. The problems of the Aral Sea, caused by irrational planning of the development of the region's economy, led to a decrease in sea level, a decrease in its volume, an increase in salt content in water, the growth of various diseases. Immunity is a set of protective reactions of the body, which are directed against genetically foreign substances. Antibodies are gammaglobulins, which have the ability to bind to homologous antigens, while causing lysis of microbes and penetrate physiological barriers. Monitoring of immunoglobulins of various classes, these studies are of particular relevance with the current situation. Keywords: immune system, region, Priaralye, immunoglobulins, antibodies

The functional state of the visual system of higher school students in conditions of stable intensification (technical, informational, social) is advisable, provided that its effectiveness is achieved. It reflects not so much the efficiency of the functional system of the organism, which characterizes the achievement of the consequence, expressed in a specific result, as the property of the system itself to fulfill the set goal under the given conditions with the required quality. The problem of the state of the visual system of students as a common resource of the visual analyzer is transferred to the field of psychophysiology and pedagogy. Indicators of the effectiveness of the state of the visual system of students characterize the degree of adaptability of the system to the performance of the assigned tasks and are generalizing indicators of the optimal functioning of the visual system. In psychophysiological research of an applied nature, such indicators are considered to be the functional level of the system, the stability of the reaction and the level of its functional capabilities as predictors of the sensory state. A particularly productive area of psychophysiological research of vision in this regard can be the study of the distribution physiological conditions of the visual system. In general, scientific research of the visual system as a resource for information processing is developing similarly to the research of the visual analyzer. In the models of the selection education system, the concept of the visual process as a filtering mechanism for the selection of information has not been sufficiently studied. In resource models, the theories of the resources of the visual system as sensory perception have come to replace the common nonspecific resources.

Taking into account the ever-increasing role of prevention in modern conditions, a comprehensive understanding of the morph physiological and chronobiological organization of human life is necessary, which is most optimal for living in specific environmental conditions, in other words, the conditions for the formation of population health and its pathological deviations due to factors that exist in the very organism, as well as acting on it from the outside. The process of cleansing the body of denatured, aged proteins occurs in many organs, primarily in the liver. Degradation processes in a cell can both recognize proteins to be degraded and begin degradation, but these processes must be selective, since there is significant heterogeneity in the rates of degradation of various proteins in one cell. Proteases are usually required for the implementation of catabolic processes, and apparently, lysosomal and extra-lysosomal proteases are involved in the catabolism of cellular proteins. The concentration of total protein and its fractions in the blood plasma in people living in various districts of the Kyzylorda region does not depend on the severity of the action of extreme factors characteristic of the Aral Sea zone.