Introduction:Anemia of chronic disease is defined as anemia occurring in chronic infections, inflammatory conditions or neoplastic disorders that are not due to marrow deficiencies or other diseases, and occurring despite presence of adequate iron stores and vitamins. Methods: A total of 40 patients were selected for the study. Participants were divided into two groups viz group A (test group; n=20) with moderate to severe periodontitis and group B (control group; n=20) with periodontally healthy subjects. The patients chosen for the study had at least 30% or more of teeth having greater than or equal to 4 mm probing depth. Clinical parameters like gingival index (GI), Sulcus Bleeding Index (SBI), plaque index (PI),probing pocket depth (PD) and clinical attachment levels (CAL) were recorded for all the patients and blood parameters (hemoglobin and red blood cell count) were determined from peripheralblood samples. The results were analyzed statistically. Results: The mean values of hemoglobin (Hb) and red blood cell (RBC) count were significantly reduced in test group as compared to control group. Conclusion: A positive relationship was observed between the blood parameters viz. Hb, RBC count, and the severity of the chronic periodontal disease. Like other chronic conditions, periodontitis can tend towards anemia showing their association. Keywords: Anemia, Chronic Periodontitis, Hemoglobin (Hb), Red Blood Cell Count (RBC Count).

Background: As with many chronic infections, the initiation and progression of periodontal diseases are modified by local and systemic host conditions, or risk factors, that markedly affect the resistance of the host to infecting periodontal pathogens. There are large number of factors including genetic, environmental, and psychosocial which constitute a substantial risk in the development of periodontal destructive diseases. Aim: The aim of present study was to scrutinize the relationship between clinical depression, sleep quality and severity of periodontitis using clinical parameters and a depression and sleep quality rating scale. Materials and Methods: Hundred patients were enrolled in this case-control study, of which 50 patients diagnosed with chronic periodontitis were categorized into cases and 50 patients who were systemically and periodontally healthy were designated as controls. The periodontal parameters recorded included probing depth and simplified oral hygiene index (OHI-S). Depression was determined using Beck’s depression scale. Pittsburgh Sleep Quality Index (PSQI) was used for scrutinizing sleep quality. Results: Self‑reported scoring of depression and sleep quality by using Beck’s depression inventory and Pittsburgh Sleep Quality Index questionnaire has revealed that patients diagnosed with chronic periodontitis had an appreciable elevated score of depression and poor sleep quality than normal controls. Conclusion: Findings of this case-control study revealed a statistically significant relationship between depression, its associated oral health behavior, sleep deprivation experienced and severity of destructive periodontal diseases.

Introduction: Periodontal disease’s initiation and propagation is through a dysbiosis of the commensal oral microbiota. But recently, through the extraordinary progress, the inter-relationship that exists between periodontal disease and systemic health has been unveiled. Through various studies. it has been revealed that vitamin D deficiency may be associated with a greater risk of developing chronic periodontitis and vitamin D supplementation may help to preserve periodontal health. Aim: To find a co-relation between 25-hydroxy vitamin D status and the severity of periodontal diseases. To evaluate and compare the effect of non-surgical periodontal therapy alone and in combination with vitamin D supplementation in reducing the severity of periodontal diseases. objective: o find a co-relation between 25-hydroxy vitamin D status and the severity of periodontal diseases. • To evaluate and compare the effect of non surgical periodontal therapy alone and in combination with vitamin D supplementation in reducing severity of periodontal diseases. Materials And Method: The present study was conducted on 90 non-menopausal female subjects divided into 3 groups. Group I comprised of healthy controls. Group II comprised of patients with moderate chronic periodontitis who were assigned to receive only Scaling and root planing (SRP). While group III included patients with moderate chronic periodontitis who were assigned to receive SRP along with Vitamin D supplementation. The periodontal parameters and serum levels of 25-hydroxy vitamin D were recorded for all the participants at baseline. Group II and group III participants were reassessed at an interval of 3 months post-treatment. Results: The results indicated that vitamin D deficiency affected periodontal health negatively. Statistically highly significant improvement was observed in Group III as compared to group II, signifying the efficacy of vitamin D supplementation adjunctive to SRP. result: The results indicated that vitamin D deficiency affected periodontal health negatively. Statistically highly significant improvement was observed in Group III as compared to group II, signifying the efficacy of vitamin D supplementation adjunctive to SRP. Conclusion: Regular evaluation of Vitamin D levels and supplementation to treat the deficiency may have potential periodontal health benefits. conclusion: Regular evaluation of Vitamin D levels and supplementation to treat the deficiency may have potential periodontal health benefits. other: nil

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