As a significant public health disease, the Hepatitis C virus (HCV) infects more than 185 million worldwide. Chronic infections are led by 170 million illnesses, resulting in 350,000 because of liver and cirrhosis cancer. Injuring of chronic liver from several insults leads to occur fibrosis. For example, metabolic disease (nonalcoholic fatty liver disease), infections (hepatitis B [HBV] and C viruses [HCV]), and toxins (alcohol). This study evaluates the knowledge and awareness about Of Chronic Hepatitis C and Liver Fibrosis among Health Care Workers and other domains of workers in Iraq. This study was carried out as cross-sectional research in Diyala, Iraq, from February / 2021 to January / 2022. In this work, 350 persons participated; the age range was (18-62) years, with a mean age of (25.9 + 9.79). The participants consisted of 100 males and 250 females. Also, they were divided into two groups: groups I and II. I (health care workers group) consists of 200 students studying in the medical department of Baquba technical institute and workers in Diyala hospitals ). Group II (other domains Workers) includes (100) participants who work in several domains. Similar to previous studies, a questionnaire was adopted to collect this research data. The outcomes demonstrate higher knowledge about HCV, Liver fibrosis, transmission, and a vaccine was noticed with a statistically significant difference among females compared to males. Regarding residency, the ability of HCV and liver fibrosis in Q1, Q2, and Q5 only among Health Care Workers compared to other domains Workers with a statistically significant difference (P<0.05). Keywords: Chronic Hepatitis C, Liver Fibrosis, Health Care Workers and other domains Workers
One of the main viruses that affect people, the Coronavirus, primarily targets the respiratory system. Animals could also be infected by Coronaviruses causing a group of respiratory and gastrointestinal severe diseases. After severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the third epidemic coronavirus. SARS-CoV-2 causes Coronavirus Disease 2019 or what so called (COVID-19). Since its first confirmation in December 2019, the spreading of COVID-19 has generated a great interest in all the world. Patients who are severely infected with COVID-19 are susceptible to hyper inflammation (HI), that accompanied biomarkers (BMs) could be useful for risk stratification (RS). Aim and Objective of the Study:The aim of the presented study is to identify some BMs including: Interleukin-6 (IL)-6, Lactate Dehydrogenase Hormone (LDH), D-dimer, Procalcitonin (PCT), Ferritin, and C-reactive protein (CRP), in patients infected with SARS-CoV-2. Materials and Methods:Serum samples were taken from patients in Diyala Governorate-Iraq during the period of January to April 2021. After detection of the virus through using of real time-PCR technique, the level of the BMs in study groups have been measured. Results:The current study revealed highly significant relationship between some of the studied BMs in the mean concentrations in the serum of the patients and control group. Conclusion:The studied BMs have been accompanied with poor outcomes. They could be the main concerns for RS models in testing of severe COVID-19 (S-COVID-19) and guiding the appropriate clinical care.
Renal failure (RF) is common disease, it is decrease of kidney function, glomerular filtration rate (GFR) this use to estimate the kidney function reduction usually is less than 60 mL / min, depending on global Burden of Disease, and the disease is ninth cause of death in the world, According to the global Burden of Disease. Our study is investigated in the relationship between IL-17F (rs763780) genes polymorphic variants in renal failure patients in Iraq. This study was accompanied around Iraqi renal failure patients, the period from February to November 2018. This study included 70 patients from Abn-Sina Center for dialysis and kidney disease, and 30 healthy controls. Tetra-primer ARMS-PCR is rapid, effective and developed assay used our study for studying in genotyping polymorphism of IL-17F (rs763780) genes. Result of our report including the correlation between the genotypes of IL-17F (rs763780) and the incidence of renal failure, as the results show a non-marked difference between patients and controls when genotype T/T (OR = 0.75). Also, no significant difference between patients and control when genotype C/C (OR = 0.85), while the genotype T/C (OR = 2.23) show important difference between control and patients more than two times. In conclusion, IL-17F play an essential role as pro-inflammatory cytokine in renal failure patients and development disease.
The modern-day study objectives at assessing the in-vitro usage of extracts of Echinacea to evaluate their inhibitory effect on pathogenic microorganisms (7 species) were isolated from different environments The methanolic crude extract of leaves of Echinacea purpurea were prepared using soxhlet apparatus. These extracts were examined to inhibited microbial strains like Pseudomonas aeruginosa, S. aureus, Klebsiella pneumonia, E. coli, Streptococcus epidermidis, Aspergillus niger, and C. albicans using the disc diffusion method. Methanol extract is more effective against resistance zone 14 mm against streptococcus. Against the MCF7 cell line, this percentage was increased after 48 hours. To consider the cytotoxic properties of herbal extract alongside human breast cancer (MCF7) cell lines with a concentration range of Echinacea purpurea extracts (6.25,12.5, 25,50,100,400 g/ml). With the maximum percentage increase resistance (97%) observed in treatment with 400mg / ml against the MCF7 cell line. The lowest ratios were discussed with MCF7 having a permanent cure (20%) at 12.5 mg/ml. Finally, GC mass analysis was performed for crude extracts to identify the most active chemical compounds of Echinacea purpurea extract, resulting in the existence of 26 biologically dynamic composites, including nine composites with antioxidant and anticancer activity.
Urinary Tract Infection (UTI) is an infection every place in the urinary tract that may be in the urethra, bladder, or kidneys by microbes. Greatest UTIs are affected by bacteria, but some are affected by fungi and, in rare cases, by viruses. UTI is the most significant common infection in humans. This study deals with the prevalence of antibodies in UTI patients; this study aims to determine the level of antibodies in UTI patients and compare with healthy controls by using the radial immunodiffusion (RID) test. The study was done during the period November 2019 to April 2020 on UTI Iraqi patients. The study included 40 patients and 20 healthy controls. Results show UTI infection occurs in females more than males also; the mean age is 40 years. All the patients with UTI showed decreased IgM serum levels and increased IgG compared with the control group. IgG, IgG, and IgM showed high significance between two UTI patients and the control group groups, while IgM doesn’t show significant differences between study groups.
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