IntroductionThe incidence of damage to the individual cranial nerves and their branches associated with laryngeal mask airway use is low; there have been case reports of damage to the lingual nerve, hypoglossal nerve and recurrent laryngeal nerve. To the best of our knowledge we present the first reported case of inferior alveolar nerve injury associated with laryngeal mask airway use.Case presentationA 35-year-old Caucasian man presented to our facility for elective anterior cruciate ligament repair. He had no background history of any significant medical problems. He opted for general anesthesia over a regional technique. He was induced with fentanyl and propofol and a size 4 laryngeal mask airway was inserted without any problems. His head was in a neutral position during the surgery. After surgery in the recovery room, he complained of numbness in his lower lip. He also developed extensive scabbing of the lower lip on the second day after surgery. The numbness and scabbing started improving after a week, with complete recovery after two weeks.ConclusionWe report the first case of vascular occlusion and injury to the inferior alveolar nerve, causing scabbing and numbness of the lower lip, resulting from laryngeal mask airway use. This is an original case report mostly of interest for anesthetists who use the laryngeal mask airway in day-to-day practice. Excessive inflation of the laryngeal mask airway cuff could have led to this complication. Despite the low incidence of cranial nerve injury associated with the use of the laryngeal mask airway, vigilant adherence to evidence-based medicine techniques and recommendations from the manufacturer's instructions can prevent such complications.

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Objective: To compare the mean induction dose of Propofol to induce general anesthesia by conventional method versus mean induction dose after applying priming principle. Study Design and Setting: Randomized controlled trial at Operation theatre complex, Shalamar Hospital, Lahore from November 2016 to May 2017. Methods: A total of 100 patients aged 18-55 years were equally divided into control and study groups. After standard anesthetic monitoring, intravenous propofol was used for induction of general anesthesia by conventional method in Control (C) group and by applying Priming principle in Study (S) group. Total dose requirement of propofol was noted. Data was analyzed in SPSS version 20 and paired sample t-test was applied. P-value of < 0.05 was considered as significant. Results: The mean induction dose of propofol was 70.90 ± 16.77 mg in study group (S) as compared to 94.60 ± 20.22 mg in the control group (C). The difference of mean induction dose in both groups was 23.7± 3.45 mg and thus p-value of 0.000. Conclusion: There was significant reduction of dose of propofol required to induce general anesthesia in elective surgical patient by applying priming principle

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