This paper gives optical design considerations and experimental results of a 20-stage digital light beam deflector consisting of a series of nitrobenzene Kerr cells and birefringent calcite prisms. The laser beam is deflected into a two-dimensional raster of 1024 by 1024 positions with a deflection rate of 500 kHz. The optical transmission of the deflector itself is 79% for green laser light. Data about background light and resolution as well as display examples showing alphanumerics and graphics are given.
SummaryThe clinical course of a young patient is described who developed a thrombophlebitis migrans associated with pulmonary embolism after a pneumonia. Circulating antibodies against fibrinogen were found, and the possible mechanisms of the formation of these antibodies, as well as the possible role of these antibodies in the development of the thrombophlebitic process are discussed. A combined intravenous therapy with heparin and steroids in high doses was successful in eliminating a further antibody production and clotting.
Background/Objectives: Muscle biopsies are requested for the workup of myopathy when less invasive workup is inconclusive. We set forth to build a multivariate model of preoperative testing to increase the odds of diagnostic and therapeutic yield of a muslce biopsy.
Methods:A 5-year retrospective chart review of 106 patients who underwent muscle biopsy was performed to evaluate preoperative workup including: magnetic resonance imaging, electromyography, muscle strength testing and laboratory evaluation including creatine kinase level, lactate level, urine myoglobin, acetylcholinesterase antibody testing, genetic testing or use of steroids in the preoperative period using Student's two-tailed t-test, two-tailed Fisher's exact test and multivariate regression model.
Results:We found an overall biopsy diagnostic pathologic yield of 47% and therapeutic yield of 88%. None of the variables reached a level of significance of p-value < 0.05 in univariate testing. In the multivariate model preoperative use of steroids and creatine kinase were the closest predictors of diagnostic and therapeutic yield but failed to reach statistical significance.
Conclusions:The therapeutic impact of muscle biopsies appears to be much greater than the diagnostic pathologic yield and the therapeutic impact larger than previously reported when rigorously defined. We were unable to create a statistically significant preoperative predictive model for muscle biopsy diagnostic and therapeutic yield.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.