Among hospitalized patients, the most common nosocomial infection is Urinary tract infection (UTI). The knowledge about the type of pathogens responsible for UTI and susceptibility and resistance pattern of the causative agents at a specific area may help the doctors to choose correct treatment regimen. This study was aimed to investigate the antibiotic susceptibility and resistance pattern of isolated urinary pathogens. This study was done at Anwer Khan Modern Medical College Hospital, Dhaka during January- June, 2011. Out of 498 clinical samples of urine collected, 245 (49.19%) showed significant bacterial growth. The most common pathogens isolated were Escherichia coli (142, 58.0%), Streptococcus feacalis (38, 15.5%), Pseudomonus (20, 8.2%), Klebsiella species (20, 8.2%) and Staphylococcus epidermidis (14, 5.7%). Members of the Enterobacteriaceae were 75%-100%sensitive to Amikacin and Nitrofurantoin while they were found variably sensitive to other commonly used antibiotics. Pseudomonas species were found 90% sensitive to Meropenem and 70% to Amikacin. Strep. feacalis were found 94.7% sensitive to Amoxicillin, 84.2% to Amoxiclave and 78.9% to Ciprofloxacin, 65.5% to Cephalexin, 50% to Ceftriaxone. The clinicians should use Meropenem and Amikacin selectively in cases of un-responsiveness to commonly used antibiotics. Anwer Khan Modern Medical College Journal Vol. 4, No. 2: July 2013, Pages 23-27 DOI: http://dx.doi.org/10.3329/akmmcj.v4i2.16938

microbial culture of urine. The dip stick method used in many centres serves only as a screening method but culture is needed for final diagnosis 7 . In almost all cases of nosocomial UTI, there is a need to start treatment before the final microbiological results are available. knowledge about the types of pathogens responsible for UTIs and their resistance pattern may help the clinician to choose the correct empirical treatment.Studies from India, Bangladesh and Nepal have reported an increased resistance of the urinary pathogens to commonly used antibiotics [8][9][10] .

Introduction: Nosocomial infections have been described as an important issue among intubated patients which leads to significant morbidity and mortality. The pattern of microbiological colonization and antibiotic resistance are much valuable in this regard. Objectives: The aim of present study was to determine the pattern of aerobic bacteria isolated from endotracheal tubes in adult patients and determination of their antimicrobial susceptibility patterns. Materials and Methods: Specimens were collected from tracheal tubes of patients with endotracheal aspiration and microbiological investigations were done. The isolated bacteria were identified by using standard cultural and biochemical tests. Then antibiotic susceptibility testing was performed on the isolates by disc diffusion method according to clinical and laboratory Standards Institute (CLSI) guideline. Results: Among 104 participants 68 (65.4%) were female and 36 (34.6%) were male. Most of the patients were in the age group of 71-80 years (48.0%). From 104 positive growths, both Gram positive and Gram negative organisms were found. Maximum samples showed growth of gram negative organism. Antimicrobial susceptibility testing revealed that the most resistant Gram negative isolate was Klebsiella with highest resistance against Vancomycin (40.4%) and which showed highest sensitive against Cefotetan, Cefoxitin and Norfloxain (39.4%). Conclusions: It may be concluded that this study indicates the emergence of antibiotic resistant infections in the studied hospital. So, there is a need to improve the effectiveness of integrated infection control programs to control and manage nosocomial infections caused by highly resistant organisms. KYAMC Journal. 2021;12(3): 153-160