Paramagnetic, luminescent, and temperature/pH-responsive polymeric particles with MR/optical imaging and antitumor drug delivery capability are prepared by emulsifier-free emulsion polymerization.
Multifunctional nanocomposites based on BaGdF nanoparticles (NPs) and metal phenolic network (MPN) have been engineered as novel contrast agents for potential applications in X-ray computed tomography, magnetic resonance and luminescence imaging. The BaGdF@MPN nanocomposites were synthesized at room temperature by coating BaGdF NPs with europium-phenolic network, which was obtained by the coordination of europium (III) with tannic acid (TA). The in vitro cytotoxicity assays against HepG2 cells revealed that the BaGdF@MPN nanocomposites presented better cytocompatibility and lower cytotoxity than pure BaGdF NPs. In addition, vivid red and green luminescence can be observed by confocal laser scanning microscope (CLSM) from the BaGdF@MPN nanocomposites laden HepG2 cells under the excitation of UV (390 nm) and visible light (440 nm), respectively. The longitudinal relaxivity value (r) of the nanocomposites was 2.457 mMs. Moreover, the nanocomoposites exhibited X-ray computed tomography (CT) and T-weighted magnetic resonance (MR) imaging capacities, and the intensities of the enhanced signals of in vitro CT and MR images were proportional to the concentrations of the nanocomposites. These results indicated that the as-prepared BaGdF@MPN nanocomposites are promising contrast agents for CT/MR/luminescence imaging.
Energy is the basic driving force to promote the economic development of all countries in the world. In the face of the era of great changes unseen in a century, the world is actively deploying and developing renewable energy. However, these forms of new energy power generation are characterized by intermittency and randomness, and their unstable power characteristics and uncontrollable source capacity have negative consequences for the secure and stable operation of the electricity system. Therefore, once new energy sources are incorporated on a large scale, system reliability studies are required. The mission of the new electricity system with new resources as the main source is to adapt to the development of large-scale renewable energy and solve the three major problems of shortage of existing energy and power, pollution, and safety. In comparison to conventional electrical systems, the new power system is not a simple replacement but a revolution. Therefore, this paper studied a new type of power system based on renewable energy. Through experiments, it is concluded that the new electricity system with renewable energy sources is not only more environmentally friendly but also can save 10.5% of electricity costs and greatly improve the utilization rate of available energy.
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