SummaryBackground: Although it is generally accepted that there is an increased oxidative stress status in alcoholics, the separate relevance of oxidative stress following alcohol withdrawal is still not understood to this date. There are reports stating that the increased oxidative stress status in alcoholics may persist independently of the constant presence of alcohol intake, while on the other side, it was demonstrated that the antioxidant defense mechanism could significantly increase after alcohol withdrawal. Methods: In the present work, we were interested in studying the relevance of oxidative stress status in the alcohol withdrawal processes, by determining some oxidative stress markers (two antioxidant enzymes: superoxide dismutase -SOD and glutathione peroxidase -GPX and a lipid peroxidation maker -MDA) after one week and one month of abstinence, as compared to the baseline and a control group of subjects. Results: Our data confirmed the increased oxidative stress status in alcoholic patients and, more importantly, we de monstrated here a significant decrease of the oxidative stress status one week and one month following the withdrawal, as showed by a significant increase in the specific activity of
Background:Computer and Internet use by children and adolescents is widespread and begins at an early age. They commonly use computers for playing games, completing school assignments, email, and connecting to the Internet. On-line, the most frequent activities are school work, email, games, and finding information. We investigated factors that influence adolescents' engagement in risky Internet behavior, in particular the factors relating to development identity.Methods:All the students, aged between 15 to 18 years old, come from 7 high schools of Iasi. The authors examined the online construction of identity at 283 teenagers, who had been involved in an online activities and completed a survey to assess relationships among development identity and (a) amount of Internet use (with the identification of a possible computer addiction), (b) the interference of excessive use with school grades and social life;Results indicated that the following factors were found to be predictors of adolescents development: frequency of Internet use, frequency of chatting, parental rules, type of personal information given out, amount of inappropriate messages received, whether inappropriate websites have been visited, and type of internet advice heard.Conclusions:Our results showed a significant positive correlation between measures of Internet use and time spent online for the Internet. Implications for and development as impacted by social support networks, are discussed. Finally, Internet use was associated with identity status. These results suggest that the Internet may be an important aid for teenager as they searched for an young identity.
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Pain, especially chronic pain, is an emotional condition as well as a physical sensation. It is a complex experience that affects thought, mood, and behavior and can lead to isolation, immobility, and drug dependence.Pain is depressing, and depression causes and intensifies pain. People with chronic pain have three times the average risk of developing psychiatric symptoms — usually mood or anxiety disorders — and depressed patients have three times the average risk of developing chronic pain.The distinct and complex character of any somatic disorder reveals the importance of social and cultural influences and that of the psychological and behavioral dimensions of pain.The objective of the first study is to prove the high frequency of a depressive syndrome on a significant group of patients with general medical conditions. The second study attempts to prove the efficiency of antidepressive medication (SSRI like) in reducing the pain related symptoms using the Hamilton Depression Evaluation Scale on a significant group of patients from the “Socola” Hospital in Iasi.The findings of the two studies have a common point: the urge to include in the assessment and management protocols of any somatic disorders, pain and depression diagnostic and treatment elements, due to their algorithmic relationship.The antidepressive therapy proves its efficiency in the pain syndrome due to the analgesic properties which are not related to the timoanaleptic effect.
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