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SUMMARY The vaginal strain of the IBR‐IPV virus, V155, produced vaginitis, rhinitis, conjunctivitis and posthitis when inoculated into susceptible cattle. It did not produce a fatal encephalitis when inoculated into calves by the intracerebral route. Virus was recovered intermittently from cattle which had been inoculated by the vaginal, preputial, or intravenous routes. Virus was recovered intermittently during 117 days, 133 days and 364 days from vaginal swabs collected from heifers inoculated by the vaginal route; during 578 days from vaginal swabs and 510 days from nasal swabs collected from a pregnant heifer inoculated intravenously; and during 361 days from a bull infected by the preputial route. Apart from the period immediately following inoculation, virus was not recovered intermittently from calves inoculated by the nasal route, but these calves were under observation for a much shorter period.

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