The APS Journal Legacy Content is the corpus of 100 years of historical scientific research from the American Physiological Society research journals. This package goes back to the first issue of each of the APS journals including the American Journal of Physiology, first published in 1898. The full text scanned images of the printed pages are easily searchable. Downloads quickly in PDF format.

Experimental renal hypertension accelerated the onset and accentuated the severity of thiouracil-cholesterol atherosclerosis in dogs. Increased blood pressure and other hemodynamic changes appear to be responsible for these effects. Hypertension and sex were without significant effect on serum cholesterol, cholesterol: phospholipid ratio and low density lipoproteins. Sex had no significant effect on the incidence or severity of this experimental atherosclerosis, including coronary involvement.

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