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BACKGROUND Areca nut is the chief aetiologic agent of oral submucous fibrosis. This condition is categorised based on clinical and histological parameters. The aim of the study was to correlate the clinical and histopathological grading in oral submucous fibrosis patients. MATERIALS AND METHODS Ours was a descriptive study on 100 oral submucous fibrosis cases reported to a college in Hyderabad from June 2013 to May 2014. After obtaining consent, comprehensive history was taken and a regular clinical assessment was done. Punch biopsy was made over the lesional area and histopathological assessment was done. Based on the mouth opening, patients were clinically graded [Ranganathan and Gauri (2006)] and compared with that of histopathological grading based on Sirsat and Pindborg (1966). RESULTS More number of males were observed (5.7: 1). Correlation between the clinical and histopathological grading was insignificant. CONCLUSION In oral submucous fibrosis, different parameters are used for grading it clinically and histopathologically, hence insignificant correlation between them.