Objective. To determine the relationship between blood pressure measured during the first trimester of pregnancy and the risk of the development of gestational diabetes mellitus. Design and methods. A total of 209 pregnant women were screened for gestational diabetes mellitus between weeks 24 and 28 of gestation, as defined by WHO criteria. Blood pressure, weight and waist circumference data were obtained by review of the medical records. Results. An elevated blood pressure at first trimester of pregnancy was associated with a six-fold increase in the risk of the development of gestational diabetes mellitus (OR = 5.8, 95 % CI 1.9-17.5, p = 0.001) compared with non-hypertensive women. Arterial hypertension (including controlled forms) in the first trimester of pregnancy was followed by a three-fold (OR = 3.04, 95 % CI 1.5-6.3) increase in the risk of gestational diabetes mellitus compared with non-hypertensive women (p = 0.005). Conclusion. Obtained data indicate that women with elevated blood pressure in the first trimester of pregnancy have an increased risk of the development of gestational diabetes mellitus.
In the present work, the efficiency of the catalytic decomposition of methane-hydrogen mixture over the NiO-CuO/Al 2 O 3 catalyst was studied. The maximum CNF value of 34.9 g/g cat is observed for the temperature of 610 °C with a hydrogen inlet concentration of 13 vol.%. The simulation of the process was performed using the kinetic model based on the mechanism of the dissociative adsorption of methane on the nickel-copper catalyst. The defined kinetic constants for this model provide an appropriate fitting of the experimental points. It was found that the optimal value of residence time at 610 °C is equal to 3.23×10 -3 s.
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