The widespread formation of unfavorable environmental, the swiftness of modern life with large information and psycho-emotional loads and extremely natural and climatic cataclysms, as well as harmful addictions and wrong way of life of modern human, lead to the development of stress and disruption of the mechanisms of adaptation of the human body and its accelerated wear. This stimulates the development of research on the creation of new methods of integrated assessment of health and quantitative assessment of the aging processes of the body systems and the whole body, as well as the possibilities of new methods of risk assessment of climatic and environmentally related pathological and age-related diseases. The aim of the work was to consider the methodology of quantitative assessment of individual health and the rate of aging of the human body on the basis of the system index of Biological age (BA); description of its essence and structure, requirements for tests - biomarkers of aging used as the index of BA, definition of possibilities and scope of application of the BA method in modern practice of Biomedicine. The use of modern methods of scientific analysis - a systematic approach to the analysis of the processes of human aging and determine its quantitative side - the value of BA, allows a reasonable approach to the choice of the number of BM, to take into account their information content and precision, and the cost of diagnostics and availability for different users, to take into account the specific objectives of the researcher. The use of the index-partial BA allows individual approaching the choice of biomarkers and create personalized panels for the definition of BA programs for the prevention of aging in personalized preventive medicine. The complexity of the content and calculation of indices of BA requires automation and the use of methods of modern computer science and computer calculations and programs. For this purpose, we have created special computer software for diagnosing aging by calculating the BA indices with the possibility of choosing BM and automatic calculation of indicators and conclusions.

Aim of the study. To evaluate the effect of professional teeth whitening on the level of oral hygiene. Material and methods. A randomized controlled, prospective clinical trial was conducted in 2 groups of 30 people, in each. In group 1, professional oral hygiene and professional teeth whitening were performed using 25% hydrogen peroxide. In group 2, only professional oral hygiene was performed. Evaluated the dynamics of the hygienic index of Quigley-Hein in the modification of S. Turesky, 2 weeks, 1 month and 6 months after the procedure. Results. 6 months after the start of the study in group 1, the average value of the Quigley-Heine index in the modification of S. Turesky was significantly lower than before the at start of the study (1.24 ± 0.11 and 2.34 ± 0.14 respectively). In group 2, the index value after 6 months exceeded 2.0 and almost returned to the initial level (2.05 ± 0.06 and 2.44 ± 0.08, respectively). During the entire observation period in patients underwent professional teeth whitening, the level of oral hygiene was significantly higher than in the control group. Conclusion. Professional teeth whitening has a positive effect on the level of oral hygiene and is a significant motivating factor in maintaining oral health.

Policy management of institutes and business organizations’ activity, dealing with radiation sources, has more of a bulky and confusing complex of requirements at the present day. The requirements being very substantial, slow down economic growth of entire branches in the field of the beneficial use of radiation technologies, and, at the same time, do not provide the condition of radiation safety. Prime Minister Dmitriy Medvedev, without any coincidence, pointed out the problem during a plenary meeting as an overpressure of regulatory and supervisory bodies on the Russian private sector. According to him, the task can be solved with ‘a regulatory guillotine’. The upcoming article resembles the first attempt to analyze and sort reasons and factors, providing a glimpse of the current situation, search key elements that cause negative influence in the field taken. On the ground of analysis of regulatory documents, vast survey experience and estimation of radiation objects and technologies, authors suggest a new complex of requirements to provide radiation security, their breakdown of classes depending on danger level of radiation objects and operating with sources of ionizing radiation. The article presents the analysis of current regulatory documents on radiation hygiene field and radiation security, retrospective view on valid documents, the expertise of activity of regulatory and supervisory bodies as part of licensing of the activity with man-made sources of ionizing radiation.

The article presents the results of the evaluation of the most significant risk factors related to lifestyle and health of medical students of different courses andfaculties. The obtained data testify that out of the total number of factors that have a significant influence on the formation of bases of student's healthy lifestyle and health, the most typical are the mode of employment, the total workload, material well-being, living conditions of the majority of today's students, as well as the conditions of nutrition, physical activity, the presence or absence of such factors as smoking, frequency of consumption of alcoholic beverages.

We discuss quantum theory of fields φ defined on a (d + 1)-dimensional manifold M with a boundary B. The free action W 0 (φ) which is a bilinear form in φ defines the Gaussian measure with a covariance (Green function) G. We discuss a relation between the quantum field theory with a fixed boundary condition and the theory defined by the Green function G. It is shown that the latter results by an average over of the first. The QFT in anti-de Sitter space is treated as an example. It is shown that quantum fields on the boundary are more regular than those on anti-de Sitter space.