The article presents the data of scientific medical literature about the relationship of the oral cavity microbiota and gastrointestinal tract with atherogenic dyslipidemia and its role in the development of cardiovascular complications. The article shows the results of epidemiological studies of association level of inflammatory diseases in the oral cavity with atherogenic diseases of cardiovascular continuum. The mechanisms of periodontal microflora and its role in the formation of unstable atheromatous plaques in the vascular channel with possible clinical manifestations (ACS - MI, cerebral stroke) are discussed. The authors give their data of retrospective analysis 1000 outpatient’s cards of periodontitis patients of varying severity, depending on BMI and their relationship to the levels of carbohydrate\lipid metabolism, state of systemic inflammation and oxidative stress.

The article presents a retrospective analysis of 1000 medical records of patients suffering from CGP varying of different degree of severity, which were divided into two subgroups: BMI≥25 kg\m2 (572 patients), and BMI<25 kg\m2 (428 patients). A retrospective analysis has demenstrated a direct correlation of severity and frequency of the combination of CGP somatic disease (CVD, type 2 diabetes, diseases of the lungs and HKT ) in patients with a BMI≥25 kg/m2. The authors also presented a correlation analysis of the relationship of gravity CGP with biochemical status in 73 patients with CGP and BMI≥25 kg\m2, which conducted the study lipid - carbohydrate spectra of blood, activity state of systemic inflammation and oxidative status, the biomass of the bacterial flora of the mouth and intestines before and after treatment with the added attraction of probiotics (Simbiolakt comp.) and antioxidants (Ubiquinone comp.). The revealed high direct correlations bleeding index and severity of CGP (rIK - StHGP=0.89), BMI and bleeding index (rIMT - IR=0.79), atherogenic plasma (IA) and CGP (rIK -NA=0.72), pro-inflammatory status and BMI (rIMT - MDA=0.87) allowed the authors to conclude - CGP varying severity is independent risk factor for CVD in patients with a BMI≥25 kg\m2.